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- Table of Contents
MYBPC3 Antibodies
AND MYBPC3 ELISA kits, MYBPC3 Proteins
Many biological assays use antibodies to detect MYBPC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYBPC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYBPC3 antibodies...
Designing a Western blot for MYBPC3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MYBPC3 Western Blot GuideDesigning an IHC experiment for MYBPC3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MYBPC3 IHC GuideMYBPC3 Infographic by Boster Bio
All MYBPC3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01083-3
100 μg/vial
Cat # A01083-3
100 μg/vial
MYBPC3 Overview
Facts about Myosin-binding protein C, cardiac-type.
Myosin-binding protein C, cardiac-type (MYBPC3)
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase.
It may modulate muscle contraction or may play a more structural role. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MYBPC3 |
| Uniprot: | Q14896 |
| Entrez: | 4607 |
Family
| Belongs to: |
|---|
| immunoglobulin superfamily |
Alternative Names
Cardiac MyBP-C; CMH4; C-protein, cardiac muscle isoform; DKFZp779E1762; FHC; MYBP-C; MyBPC3; myosin binding protein C, cardiac; myosin-binding protein C, cardiac; myosin-binding protein C, cardiac-type
Molecular Weight
Mass (kDA):
140.762 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p11.2 |
| Sequence: | 11; NC_000011.10 (47331406..47352702, complement) |
Diseases
- Cardiomyopathies
- Hypertrophy
- Hypertrophic Cardiomyopathy
- Cardiomyopathy, Hypertrophic, Familial
- Sudden Cardiac Death
- Cardiac Death
- Left Ventricular Hypertrophy
- Sudden Death
- Heart Failure
- Cardiomyopathy, Dilated
- Cardiomyopathy, Familial Idiopathic
- Heart Diseases
Pathways
- Pathogenesis
- Muscle Contraction
- Translation
- Transport
- Localization
- Regulation Of Muscle Contraction
- Protein Phosphorylation
- Electron Transport
- Electron Transport Chain
- Energy Homeostasis
- Methylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYBPC3
bosterbio.com/bosterbio-gene-info-cards/MYBPC3
References
PMID: 7744002 by Gautel M., et al. Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?
PMID: 9048664 by Carrier L., et al. Organization and sequence of human cardiac myosin binding protein C gene (MYBPC3) and identification of mutations predicted to produce truncated proteins in familial hypertrophic cardiomyopathy.
2 Publications of Boster MYBPC3 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s10529-021-03148-4, Serum-derived exosomes accelerate scald wound healing in mice by optimizing cell...
- PubMed ID: 26113016, Qian C,, Gong L, Yang Z, Chen W, Chen Y, Xu Z, Wu B, Tang C, Gao F, Zeng W,. Bmc...
*More publications can be found for each product on its corresponding product page