MYBPC3 Antibodies

AND MYBPC3 ELISA kits, MYBPC3 Proteins

Many biological assays use antibodies to detect MYBPC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYBPC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYBPC3 antibodies...

We validate the specificity of these antibodies to MYBPC3 by testing them on tissues known to express MYBPC3 positively and negatively. Browse below to find the MYBPC3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYBPC3 Infographic by Boster Bio

All MYBPC3 Products

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Anti-MYBPC3 Antibody Picoband®

1 Q&As

Western blot analysis of MYBPC3 using anti-MYBPC3 antibody (A01078-1)

IHC analysis of MYBPC3 using anti-MYBPC3 antibody (A01078-1)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A01078-1
100 μg/vial

Human MyBPC3 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2324
96 wells/kit, with removable strips.

MYBPC3 Overview

Facts about Myosin-binding protein C, cardiac-type.

MYBPC3 3D structure. Source: alphafold

Myosin-binding protein C, cardiac-type (MYBPC3)

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase.

It may modulate muscle contraction or may play a more structural role. .

Gene Information

Human
Gene Name:	MYBPC3
Uniprot:	Q14896
Entrez:	4607

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

Cardiac MyBP-C; CMH4; C-protein, cardiac muscle isoform; DKFZp779E1762; FHC; MYBP-C; MyBPC3; myosin binding protein C, cardiac; myosin-binding protein C, cardiac; myosin-binding protein C, cardiac-type

Molecular Weight

Mass (kDA):
140.762 kDA

Genomic Context


Human

Location:	11p11.2
Sequence:	11; NC_000011.10 (47331406..47352702, complement)

Diseases

Cardiomyopathies
Hypertrophy
Hypertrophic Cardiomyopathy
Cardiomyopathy, Hypertrophic, Familial
Sudden Cardiac Death
Cardiac Death
Left Ventricular Hypertrophy
Sudden Death
Heart Failure
Cardiomyopathy, Dilated
Cardiomyopathy, Familial Idiopathic
Heart Diseases

Ventricular Dysfunction, Left
Haploinsufficiency
Fibrosis
Hereditary Diseases
Ventricular Dysfunction
Cardiovascular Diseases
Cardiac Hypertrophy

Pathways

Pathogenesis
Muscle Contraction
Translation
Transport
Localization
Regulation Of Muscle Contraction
Protein Phosphorylation
Electron Transport
Electron Transport Chain
Energy Homeostasis
Methylation

Rna Stabilization
Flight
Sensitization
Mrna Splicing
Cell Motility
Lipid Storage

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYBPC3

References

PMID: 7744002 by Gautel M., et al. Phosphorylation switches specific for the cardiac isoform of myosin binding protein-C: a modulator of cardiac contraction?

PMID: 9048664 by Carrier L., et al. Organization and sequence of human cardiac myosin binding protein C gene (MYBPC3) and identification of mutations predicted to produce truncated proteins in familial hypertrophic cardiomyopathy.

1 Publications of Boster MYBPC3 Antibodies & ELISA Kits

PubMed ID: 26113016, Qian C,, Gong L, Yang Z, Chen W, Chen Y, Xu Z, Wu B, Tang C, Gao F, Zeng W,. Bmc...

*More publications can be found for each product on its corresponding product page