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- Table of Contents
MARCKS Antibodies
AND MARCKS ELISA kits, MARCKS Proteins
Many biological assays use antibodies to detect MARCKS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCKS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCKS antibodies...
Designing a Western blot for MARCKS? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MARCKS Western Blot GuideDesigning an IHC experiment for MARCKS? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MARCKS IHC GuideMARCKS Infographic by Boster Bio
All MARCKS Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A04133-4
100 μg/vial
Cat # A04133-4
100 μg/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2453
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2453
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1351
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1351
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS065108
20 µg, 100 µg
Cat # LS065108
20 µg, 100 µg
MARCKS Overview
Facts about Myristoylated alanine-rich C-kinase substrate.
Myristoylated alanine-rich C-kinase substrate (MARCKS)
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin.
MARCKS is a filamentous (F) actin cross-linking protein. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MARCKS |
| Uniprot: | P29966 |
| Entrez: | 4082 |
Family
| Belongs to: |
|---|
| MARCKS family |
Alternative Names
80K-L protein; 80K-L; FLJ14368; MACS; MACSmyristoylated alanine-rich C-kinase substrate; MARCKS; MRACKS; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); myristoylated alanine-rich protein kinase C substrate; phosphomyristin; PKCSLFLJ90045; PRKCSL; Protein kinase C substrate, 80 kDa protein, light chain
Molecular Weight
Mass (kDA):
31.555 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q21 |
| Sequence: | 6; NC_000006.12 (113857345..113863475) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.
Diseases
- Tissue Adhesions
- Neoplasms
- Nervousness
- Malignant Neoplasms
- Neuroblastoma
- Inflammation
- Cell Transformation, Neoplastic
- Asthma
- Bipolar Disorder
- Glioma
- Alzheimer's Disease
- Neoplasm Metastasis
- Lung Diseases
Pathways
- Secretion
- Exocytosis
- Protein Phosphorylation
- Localization
- Cell Proliferation
- Cell Migration
- Cell Adhesion
- Cell Growth
- Cell Motility
- Transport
- Cell Cycle
- Cell Differentiation
- Phagocytosis
PTMs
- Phosphorylation
- Myristoylation
- Cleavage
- Dephosphorylation
- Ribosylation
- Acylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCKS
bosterbio.com/bosterbio-gene-info-cards/MARCKS
References
PMID: 1860846 by Harlan D.M., et al. The human myristoylated alanine-rich C kinase substrate (MARCKS) gene (MACS). Analysis of its gene product, promoter, and chromosomal localization.
PMID: 1427823 by Sakai K., et al. Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: major substrate for protein kinase C.