This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Mast2 Antibodies
AND Mast2 ELISA kits, Mast2 Proteins
Many biological assays use antibodies to detect Mast2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mast2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mast2 antibodies...
Designing an IHC experiment for Mast2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MAST2 IHC GuideMast2 Infographic by Boster Bio
All Mast2 Products
Product
Figures
Specificity
Applications
Price
Mast2 Overview
Facts about Microtubule-associated serine/threonine-protein kinase 2.
Microtubule-associated serine/threonine-protein kinase 2 (Mast2)
Appears to link the dystrophin/utrophin network with microtubule filaments through the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.
Functions in a multi-protein complicated in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Mast2 |
| Uniprot: | Q60592 |
| Entrez: | 17776 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
EC 2.7.11; EC 2.7.11.1; FLJ39200; KIAA0807RP4-533D7.1; MAST205microtubule associated testis specific serine/threonine protein kinase; microtubule associated serine/threonine kinase 2; microtubule-associated serine/threonine-protein kinase 2; MTSSK
Molecular Weight
Mass (kDA):
190.534 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 4|4 D1 |
| Sequence: | 4; |
Tissue Specificity
Detected in round spermatids and residual bodies but not epididymal spermatozoa (at protein level). Expressed in adult but not fetal testis with levels increasing in parallel with testicular development. Also expressed at high levels in heart, lower levels in all other tissues tested.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Mastitis
- Neoplasms
- Claudication (finding)
- Mammary Neoplasms
- Mastitis, Bovine
- Metabolic Diseases
- Rabies (disorder)
- Cattle Diseases
- Instabilities, Chromosomal
Pathways
- Cell Division
- Protein Phosphorylation
- Lactation
- Localization
- Virulence
- Rna Splicing
- Cytokinesis
- Methylation
- Regeneration
- Cell Cycle
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mast2
bosterbio.com/bosterbio-gene-info-cards/Mast2
References
PMID: 8246979 by Walden P.D., et al. A novel 205-kDa testis-specific serine/threonine protein kinase associated with microtubules of the spermatid manchette.
PMID: 8902215 by Walden P.D., et al. Increased activity associated with the MAST205 protein kinase complex during mammalian spermiogenesis.