This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Mfsd2a Antibodies
AND Mfsd2a ELISA kits, Mfsd2a Proteins
Many biological assays use antibodies to detect Mfsd2a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mfsd2a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mfsd2a antibodies...
Designing a Western blot for Mfsd2a? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MFSD2A Western Blot GuideMfsd2a Infographic by Boster Bio
All Mfsd2a Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01967-2
100 μg/vial
Cat # A01967-2
100 μg/vial
Mfsd2a Overview
Facts about Sodium-dependent lysophosphatidylcholine symporter 1.
Sodium-dependent lysophosphatidylcholine symporter 1 (Mfsd2a)
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function (PubMed:24828044, PubMed:24828040). Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain.
Transport of LPC is essential because it constitutes the significant mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Mfsd2a |
| Uniprot: | Q9DA75 |
| Entrez: | 76574 |
Family
| Belongs to: |
|---|
| major facilitator superfamily |
Alternative Names
FLJ14490; FLJ35904; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; major facilitator superfamily domain-containing protein 2A; MFSD2
Molecular Weight
Mass (kDA):
58.984 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 4|4 D2.2 |
| Sequence: | 4; |
Tissue Specificity
Widely expressed. Exhibits an oscillatory pattern of expression in brown adipose tissue and liver consistent with a circadian rhythm. Enriched in brain micro-vessels, where it is specifically present in endothelium constituting the blood- brain barrier (at protein level) (PubMed:24828044, PubMed:24828040).
Diseases
- Malignant Neoplasms
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Malignant Neoplasm Of Lung
- Neoplasms
- Dysequilibrium Syndrome
- Adenocarcinoma
- Malignant Neoplasm Of Breast
- Ataxia
- Hypoxia
Pathways
- Methylation
- Protein Palmitoylation
- Circadian Rhythm
- Cell Cycle
- Glycosylation
- Hypersensitivity
- Placenta Development
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mfsd2a
bosterbio.com/bosterbio-gene-info-cards/Mfsd2a
References
PMID: 18694395 by Angers M., et al. Mfsd2a encodes a novel major facilitator superfamily domain- containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.
PMID: 23209793 by Berger J.H., et al. Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism.