Mlip Antibodies

AND Mlip ELISA kits, Mlip Proteins

Many biological assays use antibodies to detect Mlip, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mlip in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mlip antibodies...

We validate the specificity of these antibodies to Mlip by testing them on tissues known to express Mlip positively and negatively. Browse below to find the Mlip antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Mlip? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MLIP IHC Guide

Mlip Infographic by Boster Bio

All Mlip Products

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Product

Figures

Specificity

Applications

Price

Anti-MLIP Antibody

Western blot analysis of MLIP in 293 cell lysate with MLIP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Human

ELISA, IF, IHC-P, WB

$481
Cat # A12261
0.1 mg

MLIP (NM_138569) Human Over-expression Lysate

Human

$960
Cat # LS090523
20 µg, 100 µg

MLIP (NM_138569) Human Recombinant Protein

Coomassie blue staining of purified MLIP protein

$1249
Cat # PROTQ5VWP3
20 µg

Mlip Overview

Facts about Muscular LMNA-interacting protein.

Muscular LMNA-interacting protein (Mlip)

Required for precocious cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays an important role in protection against cardiac hypertrophy (PubMed:26359501, PubMed:22343712, PubMed:26436652).

Acts as a transcriptional cofactor, represses transactivator activity of ISL1 and MYOCD (PubMed:22343712). .

Gene Information

Mouse
Gene Name:	Mlip
Uniprot:	Q5FW52
Entrez:	69642

Family

Belongs to:

No superfamily

Alternative Names

C6orf142; MLIP muscular LMNA-interacting protein

Molecular Weight

Mass (kDA):
29.466 kDA

Genomic Context


Mouse

Location:	9\|9 D
Sequence:	9;

Tissue Specificity

Ubiquitous but more abundantly expressed in heart, skeletal and smooth muscle (at protein level). In brain, expressed by a subpopulation of cells within the hippocampus and cortex. In heart, expressed by ventricular cardiomyocytes. Expression is higly reduced in hypertrophic hearts (PubMed:26359501, PubMed:22343712, PubMed:26436652).

Diseases

Abnormal Degeneration
Leukoencephalopathy, Progressive Multifocal
Cardiomyopathies
Pituitary Diseases
Acute Promyelocytic Leukemia
Leukemia
Muscular Dystrophy, Emery-dreifuss
Muscular Dystrophies, Limb-girdle

Cardiomyopathy, Dilated
Dystrophy
Muscular Dystrophy

Pathways

Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mlip

References

PMID: 21498514 by Ahmady E., et al. Identification of a novel muscle enriched A-type Lamin interacting protein (MLIP).

PMID: 22343712 by Huang Z.P., et al. CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy.