Mus81 Antibodies

AND Mus81 ELISA kits, Mus81 Proteins

Many biological assays use antibodies to detect Mus81, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mus81 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mus81 antibodies...

We validate the specificity of these antibodies to Mus81 by testing them on tissues known to express Mus81 positively and negatively. Browse below to find the Mus81 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Mus81? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MUS81 Western Blot Guide

Mus81 Infographic by Boster Bio

All Mus81 Products

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Specificity

Applications

Price

Anti-MUS81 Antibody Picoband®

Western blot analysis of MUS81 using anti-MUS81 antibody (A00810-1)

Flow Cytometry analysis of 293T cells using anti-MUS81 antibody (A00810-1)

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00810-1
100 μg/vial

Anti-MUS81 Antibody Picoband®

Western blot analysis of MUS81 using anti-MUS81 antibody (A00810-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A00810-2
100 μg/vial

MUS81 (NM_025128) Human Over-expression Lysate

Human

$628
Cat # LS080198
20 µg, 100 µg

Mus81 Overview

Facts about Crossover junction endonuclease MUS81.

Crossover junction endonuclease MUS81 (Mus81)

Interacts with EME1 and EME2 to form a DNA structure- specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates comprise 3'-flap structures, replication forks and nicked Holliday junctions.

May be required in mitosis for the processing of stalled or collapsed replication forks. .

Gene Information

Mouse
Gene Name:	Mus81
Uniprot:	Q91ZJ0
Entrez:	71711

Family

Belongs to:

XPF family

Alternative Names

crossover junction endonuclease MUS81; EC 3.1.22; EC 3.1.22.-; FLJ21012; FLJ44872; MUS81 endonuclease homolog (S. cerevisiae); MUS81 endonuclease homolog (yeast); SLX3 structure-specific endonuclease subunit homolog; SLX3

Molecular Weight

Mass (kDA):
61.531 kDA

Genomic Context


Mouse

Location:	19\|19 A
Sequence:	19;

Tissue Specificity

Expressed highly in testis. Expressed also in bone marrow, brain, thymus and to a lesser extent in heart and skeletal muscle, colon, kidney and spleen.

Diseases

Genomic Instability
Malignant Neoplasms
Neoplasms
Cell Invasion
Bloom Syndrome
Fanconi Anemia
Chromosomal Translocation
Anemia
Cytogenetic Abnormality
Carcinoma
Cell Transformation, Neoplastic
Leukemia
Instabilities, Chromosomal

Acute Promyelocytic Leukemia
Lymphoma
Neoplasm Metastasis
Werner Syndrome
Malignant Tumor Of Colon
Chromosome Breakage
Liver Carcinoma

Pathways

Dna Repair
Dna Replication
Meiosis
Cell Cycle
S Phase
Chromosome Segregation
Dna Damage Checkpoint
Hypersensitivity
Gene Conversion
Strand Invasion
Mismatch Repair
Double-strand Break Repair
Recombinational Repair

Mitosis
Cell Death
Sporulation
Localization
Mitotic Cell Cycle
Cell Proliferation
Pathogenesis

PTMs

Cleavage
Phosphorylation

Ubiquitination
Methylation

Research Areas

DNA Repair
Homologous Recombination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mus81

References

PMID: 11741546 by Chen X.-B., et al. Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.

PMID: 14609959 by Abraham J., et al. Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.