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- Table of Contents
Myosin-14 Antibodies
AND Myh14 ELISA kits, Myosin-14 Proteins
Many biological assays use antibodies to detect Myosin-14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myosin-14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myosin-14 antibodies...
Designing an IHC experiment for Myosin-14? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the MYH14 IHC GuideMyh14 Infographic by Boster Bio
All Myh14 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04528-3
100 μg/vial
Cat # A04528-3
100 μg/vial
Myh14 Overview
Facts about Myosin-14.
Myosin-14 (Myh14)
Cellular myosin that seems to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. .
.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Myh14 |
| Uniprot: | Q6URW6 |
| Entrez: | 71960 |
Family
| Belongs to: |
|---|
| TRAFAC class myosin-kinesin ATPase superfamily |
Alternative Names
DFNA4; FLJ13881; FLJ43092; KIAA2034DKFZp667A1311; MHC16; MYH14 variant protein; MYH17; MYHC; Myosin heavy chain 14; Myosin Heavy Chain; Myosin heavy chain, non-muscle IIc; myosin; myosin, heavy chain 14; myosin, heavy chain 14, non-muscle; myosin, heavy polypeptide 14; myosin-14; NMHC II-C; NMHC-II-C; Non-muscle myosin heavy chain IIc; nonmuscle myosin heavy chain II-C
Molecular Weight
Mass (kDA):
228.586 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7|7 B3 |
| Sequence: | 7; |
Tissue Specificity
Highest levels in lung, kidney, brain and colon, very low levels in liver and bladder and no expression in spleen or seminal vesicle (at protein level). Isoform 1 is expressed in liver, kidney and testis with low levels in skeletal muscle and heart. Isoform 1 and isoform 2 are expressed in brain and lung. Isoform 2 is the main isoform expressed in skeletal muscle and heart. Isoform 3 is limited to brain stem, cerebellum and spinal cord.
Diseases
- Complete Hearing Loss
- Reperfusion Injury
- Inflammatory Response
- Tissue Adhesions
- Sensorineural Hearing Loss (disorder)
- Inflammation
- Autoimmunity
- Distal Muscular Dystrophies
- Hoarseness
- Retinal Degeneration
- Weakness
- Neuromuscular Diseases
Pathways
- Localization
- Cell Adhesion
- Acute Inflammatory Response
- Cytokinesis
- Inflammatory Response
- Pathogenesis
- Meiosis Ii
- Dna Methylation
- Complement Activation
- Methylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Myh14
bosterbio.com/bosterbio-gene-info-cards/Myh14
References
PMID: 14594953 by Golomb E., et al. Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.
PMID: 19240025 by Jana S.S., et al. An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation.