NAXD Antibodies

AND NAXD ELISA kits, NAXD Proteins

Many biological assays use antibodies to detect NAXD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAXD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAXD antibodies...

We validate the specificity of these antibodies to NAXD by testing them on tissues known to express NAXD positively and negatively. Browse below to find the NAXD antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAXD Infographic by Boster Bio

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CARKD (NAXD) (NM_018210) Human Over-expression Lysate

Human

$628
Cat # LS055739
20 µg, 100 µg

NAXD Overview

Facts about ATP-dependent (S)-NAD(P)H-hydrate dehydratase.

NAXD 3D structure. Source: alphafold

ATP-dependent (S)-NAD(P)H-hydrate dehydratase (NAXD)

Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which Can Be converted to ADP.
Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme makes it possible for the repair of the two epimers of NAD(P)HX, a damaged form of NAD(P)H that's due to enzymatic or heat-dependent hydration.

Gene Information

Human
Gene Name:	NAXD
Uniprot:	Q8IW45
Entrez:	55739

Family

Belongs to:

NnrD/CARKD family

Alternative Names

ATP-dependent (S)-NAD(P)H-hydrate dehydratase

Molecular Weight

Mass (kDA):
36.576 kDA

Genomic Context


Human

Location:	13q34
Sequence:	13; NC_000013.11 (110615460..110639996)

Subcellular Localizations

Mitochondrion.

Diseases

Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 2 (PEBEL2)

Interacting Proteins

KRT31
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP5-9

NOTCH2NL
SGTA
UBQLN1

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAXD

References

PMID: 30576410 by Van Bergen N.J., et al. NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses.