NDST4 Antibodies

AND NDST4 ELISA kits, NDST4 Proteins

Many biological assays use antibodies to detect NDST4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDST4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDST4 antibodies...

We validate the specificity of these antibodies to NDST4 by testing them on tissues known to express NDST4 positively and negatively. Browse below to find the NDST4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDST4 Infographic by Boster Bio

All NDST4 Products

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NDST4 (NM_022569) Human Over-expression Lysate

Human

$960
Cat # LS064579
20 µg, 100 µg

Anti-NDST4 Antibody Picoband®

Western blot analysis of NDST4 using anti-NDST4 antibody (A11749-1)

Flow Cytometry analysis of 293T cells using anti-NDST4 antibody (A11749-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A11749-1
100 µg/vial

NDST4 Overview

Facts about Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4.

NDST4 3D structure. Source: alphafold

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (NDST4)

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar back to make N-sulfated heparosan, a necessity substrate for later alterations in heparin biosynthesis.

Has reduced deacetylase activity but high sulfotransferase activity (By similarity). .

Gene Information

Human
Gene Name:	NDST4
Uniprot:	Q9H3R1
Entrez:	64579

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; EC 2.8.2.8; Glucosaminyl N-deacetylase/N-sulfotransferase 4; HSST4; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; NDST-4; N-heparan sulfate sulfotransferase 4; N-HSST 4; NHSST4

Molecular Weight

Mass (kDA):
100.716 kDA

Genomic Context


Human

Location:	4q26
Sequence:	4; NC_000004.12 (114824122..115114133, complement)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Cardiovascular Diseases
Heart Diseases
Coronary Heart Disease
Obesity
Inflammation

Diabetes Mellitus
Dysequilibrium Syndrome

Pathways

Cell Proliferation
Translation
Aging
Lung Development

PTMs

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDST4

References

PMID: 11087757 by Aikawa J., et al. Multiple isozymes of heparan sulfate/heparin GlcNAc N- deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.