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- Table of Contents
NDUFS3 Antibodies
AND NDUFS3 ELISA kits, NDUFS3 Proteins
Many biological assays use antibodies to detect NDUFS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS3 antibodies...
Designing a Western blot for NDUFS3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NDUFS3 Western Blot GuideDesigning an IHC experiment for NDUFS3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NDUFS3 IHC GuideNDUFS3 Infographic by Boster Bio
All NDUFS3 Products
Product
Figures
Specificity
Applications
Price
Anti-NDUFS3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05867-2
100 μg/vial
Cat # A05867-2
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M05867-2
20μL, 40μL, 100μL, 200μL
Cat # M05867-2
20μL, 40μL, 100μL, 200μL
NDUFS3 Overview
Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (NDUFS3)
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimum assembly required for catalysis. Complex I works in the transport of electrons from NADH to the respiratory chain.
The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | NDUFS3 |
| Uniprot: | O75489 |
| Entrez: | 4722 |
Family
| Belongs to: |
|---|
| complex I 30 kDa subunit family |
Alternative Names
CI-30; CI-30kD; complex I 30kDa subunit; Complex I-30kD; EC 1.6.5.3; EC 1.6.99.3; EC 1.6.99.5; NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; NADH dehydrogenase-ubiquinone 30 kDa subunit; NADH-ubiquinone oxidoreductase 30 kDa subunit
Molecular Weight
Mass (kDA):
30.242 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p11.2 |
| Sequence: | 11; NC_000011.10 (47579074..47584562) |
Subcellular Localizations
Mitochondrion inner membrane.
Diseases
- Malignant Neoplasms
- Mitochondrial Diseases
- Carcinoma
- Neoplasms
- Diabetes Mellitus
- Diabetes Mellitus, Experimental
- Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
- Mammary Neoplasms
- Parkinson Disease
- Malignant Neoplasm Of Breast
- Kidney Neoplasm
- Renal Cell Carcinoma
Interacting Proteins
- NDUFA5
- NDUFA8
- NDUFS2
Pathways
- Cell Death
- Oxidative Phosphorylation
- Translation
- Transport
- Electron Transport
- Localization
- Mitochondrial Translation
- Electron Transport Chain
- Nadh Oxidation
- Membrane Hyperpolarization
- Insulin Secretion
- Proteolysis
- Mitochondrial Dna Replication
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS3
bosterbio.com/bosterbio-gene-info-cards/NDUFS3
References
PMID: 9647766 by Loeffen J., et al. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.
PMID: 10967146 by Procaccio V., et al. Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial Complex I: genomic organization and expression.