NDUFS6 Antibodies

AND NDUFS6 ELISA kits, NDUFS6 Proteins

Many biological assays use antibodies to detect NDUFS6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFS6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFS6 antibodies...

We validate the specificity of these antibodies to NDUFS6 by testing them on tissues known to express NDUFS6 positively and negatively. Browse below to find the NDUFS6 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for NDUFS6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NDUFS6 IHC Guide

NDUFS6 Infographic by Boster Bio

All NDUFS6 Products

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Product

Figures

Specificity

Applications

Price

Anti-NDUFS6 Antibody Picoband®

Western blot analysis of NDUFS6 using anti-NDUFS6 antibody (A09082-2)

IHC analysis of NDUFS6 using anti-NDUFS6 antibody (A09082-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A09082-2
100 μg/vial

Anti-NDUFS6 Antibody (Center)

Human, Mouse

$299
Cat # M09082
50 µl

NDUFS6 (NM_004553) Human Over-expression Lysate

Human

$628
Cat # LS004726
20 µg, 100 µg

NDUFS6 (NM_004553) Human Recombinant Protein

Coomassie blue staining of purified NDUFS6 protein

$1249
Cat # PROTO75380
20 µg

NDUFS6 Overview

Facts about NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial.

NDUFS6 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (NDUFS6)

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone. .

Gene Information

Human
Gene Name:	NDUFS6
Uniprot:	O75380
Entrez:	4726

Family

Belongs to:

complex I NDUFS6 subunit family

Alternative Names

CI13KDA; Complex I-13kD-A; mitochondrial respiratory chain, 13-kD subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD) (NADH-coenzyme Qreductase); NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Qreductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH:ubiquinone oxidoreductase NDUFS6 subunit; NADH-ubiquinone oxidoreductase 13 kDa-A subunit

Molecular Weight

Mass (kDA):
13.712 kDA

Genomic Context


Human

Location:	5p15.33
Sequence:	5; NC_000005.10 (1801407..1816048)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Precancerous Conditions
Cholangiocarcinoma
Acidosis
Uterine Cervical Neoplasm
Mitochondrial Diseases
Heart Failure
Leigh Disease
Acidemia
Neoplasm Invasiveness
Malignant Tumor Of Cervix

Parkinson Disease
Fibrosis
Cardiomyopathies
Malignant Neoplasms
Cervical Intraepithelial Neoplasia
Acidosis, Lactic

Pathways

Oxidative Phosphorylation
Mrna Splicing
Translation
Cell Cycle
Dna Repair
Pathogenesis

Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFS6

References

PMID: 9647766 by Loeffen J., et al. cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed.

PMID: 15372108 by Kirby D.M., et al. NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency.