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- Table of Contents
NEMF Antibodies
AND NEMF ELISA kits, NEMF Proteins
Many biological assays use antibodies to detect NEMF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEMF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEMF antibodies...
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NEMF Infographic by Boster Bio
All NEMF Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1640
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1640
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
IHC
$523
Cat # M09039
100 µl
Cat # M09039
100 µl
NEMF Overview
Facts about Nuclear export mediator factor NEMF.
Nuclear export mediator factor NEMF (NEMF)
Part of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety.
NEMF is important for the stable association of LTN1 to the complicated (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Gene Information
| Human | |
|---|---|
| Gene Name: | NEMF |
| Uniprot: | O60524 |
| Entrez: | 9147 |
Family
| Belongs to: |
|---|
| NEMF family |
Alternative Names
Nuclear export mediator factor NEMF
Molecular Weight
Mass (kDA):
122.954 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q21.3 |
| Sequence: | 14; NC_000014.9 (49782083..49853203, complement) |
Tissue Specificity
Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
Subcellular Localizations
Nucleus.
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEMF
bosterbio.com/bosterbio-gene-info-cards/NEMF
References
PMID: 9610721 by Scanlan M.J., et al. Characterization of human colon cancer antigens recognized by autologous antibodies.
PMID: 16103875 by Bi X., et al. Drosophila caliban, a nuclear export mediator, can function as a tumor suppressor in human lung cancer cells.