NFS1 Antibodies

AND NFS1 ELISA kits, NFS1 Proteins

Many biological assays use antibodies to detect NFS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NFS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NFS1 antibodies...

We validate the specificity of these antibodies to NFS1 by testing them on tissues known to express NFS1 positively and negatively. Browse below to find the NFS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for NFS1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NFS1 Western Blot Guide

NFS1 Infographic by Boster Bio

All NFS1 Products

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Product

Figures

Specificity

Applications

Price

Anti-NFS1 Antibody Picoband®

Western blot analysis of NFS1 using anti-NFS1 antibody (A05061-1)

Flow Cytometry analysis of HEL cells using anti-NFS1 antibody (A05061-1)

Immunoprecipitating NFS1 in HepG2 whole cell lysate

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, WB

$370
Cat # A05061-1
100 µg/vial

NFS1 (NM_001198989) Human Over-expression Lysate

NFS1 Human Over-expression Lysates NM_001198989

Human

$628
Cat # LS009054
20 µg, 100 µg

NFS1 Overview

Facts about Cysteine desulfurase, mitochondrial.

NFS1 3D structure. Source: alphafold

Cysteine desulfurase, mitochondrial (NFS1)

Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It provides the inorganic sulfur for iron- sulfur (Fe-S) clusters.

May be involved in the biosynthesis of molybdenum cofactor. .

Gene Information

Human
Gene Name:	NFS1
Uniprot:	Q9Y697
Entrez:	9054

Family

Belongs to:

class-V pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

cysteine desulfurase, mitochondrial; EC 2.8.1.7; NFS1 nitrogen fixation 1 homolog (S. cerevisiae); NifS; NIFShomolog); nitrogen-fixing bacteria S-like protein

Molecular Weight

Mass (kDA):
50.196 kDA

Genomic Context


Human

Location:	20q11.22
Sequence:	20; NC_000020.11 (35668052..35699352, complement)

Tissue Specificity

Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas.

Subcellular Localizations

[Isoform Mitochondrial]: Mitochondrion.; [Isoform Cytoplasmic]: Cytoplasm. Nucleus.

Diseases

Friedreich Ataxia
Ataxia
Neurodegenerative Disorders
Physiological Stress
Abnormal Degeneration
Stasis
Prion Diseases
Mitochondrial Dna Depletion
Hereditary Diseases
Degenerative Disorder
Nerve Degeneration
Iron Overload

Diabetes Mellitus
Hypokinesia
Growth Retardation
Cardiovascular Diseases
Cardiomyopathies
Malaria
Iron Deficiency

Interacting Proteins

COQ3
LYRM4

Pathways

Iron-sulfur Cluster Assembly
Localization
Translation
Biosynthetic Process
Trna Processing
Gene Silencing
Aerobic Respiration
Photosynthesis
Protein Maturation
Oxidative Phosphorylation
Embryo Development

Protein Urmylation
Nitrogen Fixation
Protein Folding
Cell Growth
Pathogenesis
Rna Interference

PTMs

Cleavage
Carboxylation

Reduction
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFS1

References

PMID: 9885568 by Land T., et al. Targeting of a human iron-sulfur cluster assembly enzyme, nifs, to different subcellular compartments is regulated through alternative AUG utilization.

PMID: 11124703 by Stanchi F., et al. Characterization of 16 novel human genes showing high similarity to yeast sequences.