NMNAT1 Antibodies

AND NMNAT1 ELISA kits, NMNAT1 Proteins

Many biological assays use antibodies to detect NMNAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NMNAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NMNAT1 antibodies...

We validate the specificity of these antibodies to NMNAT1 by testing them on tissues known to express NMNAT1 positively and negatively. Browse below to find the NMNAT1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for NMNAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NMNAT1 Western Blot Guide

Designing an IHC experiment for NMNAT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NMNAT1 IHC Guide

NMNAT1 Infographic by Boster Bio

All NMNAT1 Products

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Product

Figures

Specificity

Applications

Price

Anti-NMNAT1 Antibody Picoband®

Western blot analysis of NMNAT1 using anti-NMNAT1 antibody (A03221-1)

IHC analysis of NMNAT1 using anti-NMNAT1 antibody (A03221-1)

IF analysis of NMNAT1 using anti-NMNAT1 antibody (A03221-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A03221-1
100 μg/vial

NMNAT1 (NM_022787) Human Over-expression Lysate

Human

$628
Cat # LS064802
20 µg, 100 µg

Mouse Nmnat1 Recombinant Protein

SDS-PAGE

$350
Cat # PROTQ9EPA7
Starting from 10ug

Human NMNAT-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9HAN9
Starting from 20ug

NMNAT1 Overview

Facts about Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1.

NMNAT1 3D structure. Source: alphafold

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMNAT1)

Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency (PubMed:17402747). Can use triazofurin monophosphate (TrMP) as substrate (PubMed:17402747).

Also catalyzes the reverse reaction, i.e.

Gene Information

Human
Gene Name:	NMNAT1
Uniprot:	Q9HAN9
Entrez:	64802

Family

Belongs to:

eukaryotic NMN adenylyltransferase family

Alternative Names

EC 2.7.7.1; EC 2.7.7.18; NaMN adenylyltransferase 1; nicotinamide mononucleotide adenylyltransferase 1; nicotinamide nucleotide adenylyltransferase 1; nicotinamide nucleotide adenylyltransferase; Nicotinate-nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NMNAT1; NMNAT-1; NMNATPNAT1; PNAT1; pyridine nucleotide adenylyltransferase 1

Molecular Weight

Mass (kDA):
31.932 kDA

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (9942923..9996884)

Tissue Specificity

Widely expressed with highest levels in skeletal muscle, heart and kidney. Also expressed in the liver pancreas and placenta. Widely expressed throughout the brain.

Subcellular Localizations

Nucleus.

Diseases

Wallerian Degeneration
Nerve Degeneration
Neurodegenerative Disorders
Nervousness
Amaurosis
Leber Congenital Amaurosis
Sciatic Neuropathy
Nervous System Disorder
Alzheimer's Disease
Abnormal Degeneration
Retinal Degeneration
Nerve Damage

Malignant Neoplasms
Pituitary Diseases
Peripheral Neuropathy
Parkinson Disease
Motor Neuron Disease
Retinal Dystrophies
Optic Atrophy

Interacting Proteins

CCNC
KPNA2
SIRT1
TDO2

Pathways

Neuroprotection
Localization
Cell Death
Cell Cycle
Transport
Cell Adhesion
Cell Proliferation
Programmed Cell Death
Cellular Homeostasis
Aging
Regulation Of Gene Expression
Protein Deacetylation

Regeneration
Cellular Localization
Protein Folding
Segmentation
Pathogenesis
Rna Interference

PTMs

Ubiquitination

Phosphorylation

Deacetylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NMNAT1

References

PMID: 11248244 by Schweiger M., et al. Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis.

PMID: 11027696 by Emanuelli M., et al. Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase.