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- Table of Contents
Noggin Antibodies
AND NOG ELISA kits, Noggin Proteins
Many biological assays use antibodies to detect Noggin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Noggin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Noggin antibodies...
Designing a Western blot for Noggin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NOG Western Blot GuideNOG Infographic by Boster Bio
All NOG Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01844-2
100 μg/vial
Cat # A01844-2
100 μg/vial
Human, Mouse, Rat
ELISA, WB
$370
Cat # A02250-2
100 µg/vial
Cat # A02250-2
100 µg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01844-2
100 μg
Cat # M01844-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01804-2
100 μg
Cat # M01804-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01804-1
100 μg
Cat # M01804-1
100 μg
Human, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02250-1
100 μg
Cat # M02250-1
100 μg
Human
$628
Cat # LS116150
20 µg, 100 µg
Cat # LS116150
20 µg, 100 µg
Human
$628
Cat # LS065078
20 µg, 100 µg
Cat # LS065078
20 µg, 100 µg
NOG Overview
Facts about Noggin.
Noggin (NOG)
Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation.
Inhibits chondrocyte differentiation through its interaction with GDF5 and, likely, GDF6 (PubMed:21976273, PubMed:26643732). .
Gene Information
| Human | |
|---|---|
| Gene Name: | NOG |
| Uniprot: | Q13253 |
| Entrez: | 9241 |
Family
| Belongs to: |
|---|
| noggin family |
Alternative Names
NOG; Noggin; SYM1; symphalangism 1 (proximal); synostoses (multiple) syndrome 1; SYNS1; SYNS1A
Molecular Weight
Mass (kDA):
25.774 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q22 |
| Sequence: | 17; NC_000017.11 (56593699..56595611) |
Subcellular Localizations
Secreted.
Diseases
- Immunologic Deficiency Syndromes
- Neoplasms
- Malignant Neoplasms
- Syndactyly
- Congenital Abnormal Synostosis
- Severe Combined Immunodeficiency
- Conductive Hearing Loss
- Neoplasm Metastasis
- Ankylosis
- Congenital Combined Immunodeficiency
- Lymphoma
- Hyperopia
Interacting Proteins
- BMP2
Pathways
- Pathogenesis
- Cell Proliferation
- Cell Growth
- Secretion
- Cell Differentiation
- Ossification
- Regeneration
- Cell Cycle
- Cell Death
- Immune Response
- Gastrulation
- Cell Development
- Cell Migration
PTMs
- Phosphorylation
- Methylation
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOG
bosterbio.com/bosterbio-gene-info-cards/NOG
References
PMID: 7666191 by Valenzuela D.M., et al. Identification of mammalian noggin and its expression in the adult nervous system.
PMID: 21976273 by Schwaerzer G.K., et al. New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.
1 Publications of Boster Noggin Antibodies & ELISA Kits
- PubMed ID: 21573506, Expression of NANOG in human gliomas and its relationship with undifferentiated ...
*More publications can be found for each product on its corresponding product page