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- Table of Contents
Nucleolar protein 3 Antibodies
AND NOL3 ELISA kits, Nucleolar protein 3 Proteins
Many biological assays use antibodies to detect Nucleolar protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleolar protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleolar protein 3 antibodies...
Designing an IHC experiment for Nucleolar protein 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NOL3 IHC GuideNOL3 Infographic by Boster Bio
All NOL3 Products
Product
Figures
Specificity
Applications
Price
Human, Rat
WB
$370
Cat # PA1793
100 μg/vial
Cat # PA1793
100 μg/vial
Human
ELISA
$480
Cat # EKC1607
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1607
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS008996
20 µg, 100 µg
Cat # LS008996
20 µg, 100 µg
NOL3 Overview
Facts about Nucleolar protein 3.
Nucleolar protein 3 (NOL3)
Isoform 1: May be involved in RNA splicing. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NOL3 |
| Uniprot: | O60936 |
| Entrez: | 8996 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Apoptosis repressor with CARD; ARC; ARCFLJ35304; CARD2; Muscle-enriched cytoplasmic protein; MYC; MYP; NOL3; NOP30; NOPnucleolar protein 3; nucleolar protein 3 (apoptosis repressor with CARD domain); Nucleolar protein of 30 kDa
Molecular Weight
Mass (kDA):
22.629 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (67170497..67175737) |
Tissue Specificity
Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.
Subcellular Localizations
[Isoform 1]: Nucleus, nucleolus. The SR-rich C-terminus mediates nuclear localization.; [Isoform 3]: Cytoplasm.; [Isoform 2]: Cytoplasm. Mitochondrion. Sarcoplasmic reticulum. Membrane; Lipid-anchor. Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress.
Diseases
- Malignant Neoplasms
- Ischemia
- Hypoxia
- Neoplasms
- Infarction
- Myocardial Infarction
- Carcinogenesis
- Myocardial Reperfusion Injury
- Hypertrophy
- Anoxia
- Heart Failure
- Heart Diseases
- Myocardial Ischemia
Interacting Proteins
- CASP8
- TINF2
- TP53
Pathways
- Cell Death
- Localization
- Pathogenesis
- Induction Of Apoptosis
- Rna Interference
- Programmed Cell Death
- Aging
- Translation
- Cell Cycle
- Neuroprotection
- Mitochondrial Fission
- Mitochondrial Depolarization
- Cell Cycle Arrest
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Apoptosis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOL3
bosterbio.com/bosterbio-gene-info-cards/NOL3
References
PMID: 9560245 by Koseki T., et al. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases.
PMID: 10196175 by Stoss O., et al. Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c.