NT5C1A Antibodies

AND NT5C1A ELISA kits, NT5C1A Proteins

Many biological assays use antibodies to detect NT5C1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NT5C1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NT5C1A antibodies...

We validate the specificity of these antibodies to NT5C1A by testing them on tissues known to express NT5C1A positively and negatively. Browse below to find the NT5C1A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for NT5C1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NT5C1A IHC Guide

NT5C1A Infographic by Boster Bio

All NT5C1A Products

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Anti-NT5C1A Antibody Picoband®

Western blot analysis of NT5C1A using anti-NT5C1A antibody (A12036-2)

IHC analysis of NT5C1A using anti-NT5C1A antibody (A12036-2)

Human

ELISA, IHC, WB

$370
Cat # A12036-2
100 µg/vial

Anti-Cytosolic 5'-nucleotidase 1A NT5C1A Antibody

Immunofluorescence analysis of A549 cells, using NT5C1A Antibody

Western blot analysis of lysates from MCF-7 and HepG2 cells, using NT5C1A Antibody

Human, Mouse

ELISA, IF, ICC, WB

$335
Cat # A30631
100ul

NT5C1A Overview

Facts about Cytosolic 5'-nucleotidase 1A.

NT5C1A 3D structure. Source: alphafold

Cytosolic 5'-nucleotidase 1A (NT5C1A)

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps regulate adenosine levels in heart during ischemia and hypoxia.

Gene Information

Human
Gene Name:	NT5C1A
Uniprot:	Q9BXI3
Entrez:	84618

Family

Belongs to:

5'-nucleotidase type 3 family

Alternative Names

5'-nucleotidase, cytosolic IA; AMP-specific 5'-NT; CN1; CN1A; CN-I; CN-IA; cytosolic 5' nucleotidase, type 1A; cytosolic 5'-nucleotidase 1A; Cytosolic 5'-nucleotidase IA; EC 3.1.3.5; MGC119199; MGC119201

Molecular Weight

Mass (kDA):
41.021 kDA

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (39659121..39672038, complement)

Tissue Specificity

Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Obesity
Diabetes Mellitus, Experimental
Diabetes Mellitus

Interacting Proteins

WDYHV1

Pathways

Transport
Lipid Oxidation
Gene Silencing
Glucose Transport

PTMs

Phosphorylation

Oxidation

Dephosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NT5C1A

References

PMID: 11133996 by Hunsucker S.A., et al. Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.