Netrin-1 Antibodies

AND NTN1 ELISA kits, Netrin-1 Proteins

Many biological assays use antibodies to detect Netrin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Netrin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Netrin-1 antibodies...

We validate the specificity of these antibodies to Netrin-1 by testing them on tissues known to express NTN1 positively and negatively. Browse below to find the NTN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Netrin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NTN1 Western Blot Guide

NTN1 Infographic by Boster Bio

All NTN1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Netrin 1/NTN1 Antibody Picoband®

Anti-Netrin 1 antibody, PA1662, Western blottingLane 1: U87 Cell LysateLane 2: COLO320 Cell Lysate

Human, Mouse, Rat

$370
Cat # PA1662
100 μg/vial

Anti-Netrin 1 NTN1 Monoclonal Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Western blot analysis of Netrin 1 expression in Human fetal brain lysate

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M04892
100 μl

NTN1 Overview

Facts about Netrin-1.

NTN1 3D structure. Source: alphafold

Netrin-1 (NTN1)

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with DCC or any UNC5 receptors will lead to axon attraction or repulsion, respectively.

It also serve as a survival factor via its association with its receptors that prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Gene Information

Human
Gene Name:	NTN1
Uniprot:	O95631
Entrez:	9423

Family

Belongs to:

No superfamily

Alternative Names

netrin 1; Netrin1; Netrin-1; NTN1; NTN1Lnetrin 1, mouse, homolog of

Molecular Weight

Mass (kDA):
67.748 kDA

Genomic Context


Human

Location:	17p13.1
Sequence:	17; NC_000017.11 (9021510..9244000)

Subcellular Localizations

Secreted. Cytoplasm. Mainly secreted.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Colorectal Cancer
Neoplasm Metastasis
Hepatitis B
Neoplasm Invasiveness
Adenocarcinoma
Liver Carcinoma
Hepatitis C
Prostatic Neoplasms
Inflammation
Nervousness

Tissue Adhesions
Malignant Neoplasm Of Breast
Ataxia
Hypoxia
Dysplasia
Tumor Angiogenesis
Acute-phase Reaction

Interacting Proteins

APP
DCC
DRAXIN

Pathways

Cell Migration
Axon Guidance
Signal Transduction By P53 Class Mediator
Cell Adhesion
Negative Regulation Of Centriole Replication
Activation Of Mapk Activity
Cell Division
Cell Motility
Acute-phase Response
Cell Differentiation
Spinal Cord Development
Regulation Of Wnt Receptor Signaling Pathway
Cell Proliferation

Neutrophil Chemotaxis
Interleukin-8 Production
Humoral Immune Response
Regulation Of Peptidase Activity
Dna Replication
Cell Recognition
Regulation Of Centriole Replication

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NTN1

References

PMID: 9950216 by Meyerhardt J.A., et al. Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas.

PMID: 20736409 by Li J., et al. Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins.

2 Publications of Boster Netrin-1 Antibodies & ELISA Kits

PubMed ID: 20714878, Zhong S, Zou L, Zhao Y, Hu B, Xie H. J Huazhong Univ Sci Technolog Med Sci. 2010...
PubMed ID: 21193949, Qian-Hua W, Shao-Ping Z, Jian-Wen Z, Yun Y, Li Z. Mol Cell Biochem. 2011 Apr;350...

*More publications can be found for each product on its corresponding product page