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- Table of Contents
Facts about Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
Asymmetrically hydrolyzes Ap4A to yield AMP and ATP.
Plays a major role in maintaining homeostasis..
Human | |
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Gene Name: | NUDT2 |
Uniprot: | P50583 |
Entrez: | 318 |
Belongs to: |
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Nudix hydrolase family |
Ap4A hydrolase 1; Ap4A hydrolase; Ap4Aase; APAH1Diadenosine 5'-5'''-P1; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; diadenosine 5'-5''-P1; Diadenosine tetraphosphatase; EC 3.6.1.17; MGC10404; Nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; Nudix motif 2; P4-tetraphosphate asymmetrical hydrolase; P4-tetraphosphate pyrophosphohydrolase
Mass (kDA):
16.829 kDA
Human | |
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Location: | 9p13.3 |
Sequence: | 9; NC_000009.12 (34329506..34343713) |
PMID: 7487923 by Thorne N.M.H., et al. Human diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase is a member of the MutT family of nucleotide pyrophosphatases.
PMID: 15596429 by Swarbrick J.D., et al. Structure and substrate-binding mechanism of human Ap4A hydrolase.