Nuclear pore complex protein Nup50 (NUP50)

Component of the nuclear pore complex which has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of this importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008).

Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).