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Homeobox protein NANOG Antibodies
AND Nanog ELISA kits, Homeobox protein NANOG Proteins
Many biological assays use antibodies to detect Homeobox protein NANOG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein NANOG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein NANOG antibodies...
Designing a Western blot for Homeobox protein NANOG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the NANOG Western Blot GuideNanog Infographic by Boster Bio
All Nanog Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00153-4
100 μg/vial
Cat # A00153-4
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00153
100 μl
Cat # M00153
100 μl
Human, Mouse, Rat
ELISA, IF, IHC-P, ICC, WB
$481
Cat # A00153
0.1 mg
Cat # A00153
0.1 mg
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00153-2
20μL, 40μL, 100μL, 200μL
Cat # M00153-2
20μL, 40μL, 100μL, 200μL
Human
$628
Cat # LS360030
20 µg, 100 µg
Cat # LS360030
20 µg, 100 µg
Nanog Overview
Facts about Homeobox protein NANOG.
Homeobox protein NANOG (Nanog)
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal (PubMed:25825768). Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.
Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'- [CG][GA][CG]C[GC]ATTAN[GC]-3'.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nanog |
| Uniprot: | Q80Z64 |
| Entrez: | 71950 |
Family
| Belongs to: |
|---|
| Nanog homeobox family |
Alternative Names
FLJ12581; FLJ40451; hNanog; homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox; Nanog
Molecular Weight
Mass (kDA):
34.24 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6|6 F1 |
| Sequence: | 6; |
Tissue Specificity
Not expressed in oocytes and spermatogonia (at protein level). Not expressed in many somatic organs, ovary, testis, fibroblast and hematopoietic cell lines.
Diseases
- Neoplasms
- Malignant Neoplasms
- Teratoma
- Carcinoma
- Idiopathic Pneumonia Syndrome
- Leukemia
- Cell Transformation, Neoplastic
- Embryonal Carcinoma
- Malignant Paraganglionic Neoplasm
- Immunologic Deficiency Syndromes
- Neoplasm Metastasis
- Testicular Neoplasms
Pathways
- Methylation
- Cell Differentiation
- Cell Proliferation
- Dna Methylation
- Cell Cycle
- Regeneration
- Localization
- Demethylation
- Stem Cell Differentiation
- Cell Growth
- Pathogenesis
- Fertilization
- Rna Interference
PTMs
- Methylation
- Phosphorylation
- Demethylation
- Acetylation
- Cleavage
- Deacetylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nanog
bosterbio.com/bosterbio-gene-info-cards/Nanog
References
PMID: 12787504 by Mitsui K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.
PMID: 12787505 by Chambers I., et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells.
1 Publications of Boster Homeobox protein NANOG Antibodies & ELISA Kits
- PubMed ID: 10.1155/2021/8493431, LncRNA LINC00662 Exerts an Oncogenic Effect on Osteosarcoma by the miR-16-5p/ITP...
*More publications can be found for each product on its corresponding product page