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- Table of Contents
NAT2 Antibodies
AND NAT2 ELISA kits, NAT2 Proteins
Many biological assays use antibodies to detect NAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAT2 antibodies...
Designing an IHC experiment for NAT2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NAT2 IHC GuideNAT2 Infographic by Boster Bio
All NAT2 Products
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NAT2 Overview
Facts about Arylamine N-acetyltransferase 2.
Arylamine N-acetyltransferase 2 (NAT2)
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
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Gene Information
| Human | |
|---|---|
| Gene Name: | NAT2 |
| Uniprot: | P11245 |
| Entrez: | 10 |
Family
| Belongs to: |
|---|
| arylamine N-acetyltransferase family |
Alternative Names
AAC2N-acetyltransferase type 2; Arylamide acetylase 2; arylamine N-acetyltransferase 2; EC 2.3.1.5; N-acetyltransferase 2 (arylamine N-acetyltransferase); NAT-2; PNAT; Polymorphic arylamine N-acetyltransferase
Molecular Weight
Mass (kDA):
33.542 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p22 |
| Sequence: | 8; NC_000008.11 (18386585..18401219) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Slow Acetylator Due To N-acetyltransferase Enzyme Variant
- Malignant Neoplasm Of Urinary Bladder
- Neoplasms
- Bladder Neoplasm
- Colorectal Cancer
- Colorectal Neoplasms
- Carcinogenesis
- Carcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Tuberculosis
Interacting Proteins
- ATM
- RAD51
Pathways
- Pathogenesis
- Dna Repair
- Excretion
- Conjugation
- Hypersensitivity
- Localization
- Transport
- Sensitization
- Methylation
- Mismatch Repair
- Translation
- Dna Methylation
- Immune Response
PTMs
- Acetylation
- Hydroxylation
- Reduction
- Oxidation
- Methylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAT2
bosterbio.com/bosterbio-gene-info-cards/NAT2
References
PMID: 2734109 by Grant D.M., et al. Nucleotide sequence of an intronless gene for a human arylamine N- acetyltransferase related to polymorphic drug acetylation.
PMID: 2340091 by Blum M., et al. Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.