NAT2 Antibodies

AND NAT2 ELISA kits, NAT2 Proteins

Many biological assays use antibodies to detect NAT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAT2 antibodies...

We validate the specificity of these antibodies to NAT2 by testing them on tissues known to express NAT2 positively and negatively. Browse below to find the NAT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAT2 Infographic by Boster Bio

All NAT2 Products

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Anti-NAT2 Antibody

Western blot analysis of extracts of various cell lines, using NAT2 antibody at 1:3000 dilution

Immunohistochemistry of paraffin-embedded rat lung using NAT2 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded rat heart using NAT2 antibody at dilution of 1:100

Human, Mouse, Rat

IHC, WB

$405
Cat # A00966
100ul

NAT2 (NM_000015) Human Over-expression Lysate

Human

$628
Cat # LS000010
20 µg, 100 µg

NAT2 Overview

Facts about Arylamine N-acetyltransferase 2.

NAT2 3D structure. Source: alphafold

Arylamine N-acetyltransferase 2 (NAT2)

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

Gene Information

Human
Gene Name:	NAT2
Uniprot:	P11245
Entrez:	10

Family

Belongs to:

arylamine N-acetyltransferase family

Alternative Names

AAC2N-acetyltransferase type 2; Arylamide acetylase 2; arylamine N-acetyltransferase 2; EC 2.3.1.5; N-acetyltransferase 2 (arylamine N-acetyltransferase); NAT-2; PNAT; Polymorphic arylamine N-acetyltransferase

Molecular Weight

Mass (kDA):
33.542 kDA

Genomic Context


Human

Location:	8p22
Sequence:	8; NC_000008.11 (18386585..18401219)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Slow Acetylator Due To N-acetyltransferase Enzyme Variant
Malignant Neoplasm Of Urinary Bladder
Neoplasms
Bladder Neoplasm
Colorectal Cancer
Colorectal Neoplasms
Carcinogenesis
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Tuberculosis

Malignant Neoplasm Of Lung
Lung Neoplasms
Malignant Tumor Of Colon
5,10-methylenetetrahydrofolate Reductase Deficiency
Drug-induced Liver Injury
Malignant Squamous Cell Neoplasm
Fast Acetylator Due To N-acetyltransferase Enzyme Variant

Interacting Proteins

ATM
RAD51

Pathways

Pathogenesis
Dna Repair
Excretion
Conjugation
Hypersensitivity
Localization
Transport
Sensitization
Methylation
Mismatch Repair
Translation
Dna Methylation
Immune Response

Cell Cycle
Dna Amplification
Aging
Drug Resistance
Secretion
Limb Development
Tube Development

PTMs

Acetylation
Hydroxylation
Reduction
Oxidation
Methylation

Deacetylation
Demethylation
Phosphorylation
Biotinylation
Cleavage

Ubiquitination

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAT2

References

PMID: 2734109 by Grant D.M., et al. Nucleotide sequence of an intronless gene for a human arylamine N- acetyltransferase related to polymorphic drug acetylation.

PMID: 2340091 by Blum M., et al. Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression.