Nucleolar protein 8 Antibodies

AND NOL8 ELISA kits, Nucleolar protein 8 Proteins

Many biological assays use antibodies to detect Nucleolar protein 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nucleolar protein 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nucleolar protein 8 antibodies...

We validate the specificity of these antibodies to Nucleolar protein 8 by testing them on tissues known to express NOL8 positively and negatively. Browse below to find the NOL8 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NOL8 Infographic by Boster Bio

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Anti-Nop132 NOL8 Antibody

5 Q&As

Western Blot (WB) analysis of NIH-3T3 cells using Nop132 Polyclonal antibody

Western Blot (WB) analysis of 3T3 cells using Nop132 Polyclonal antibody

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A10985
100μl

NOL8 (NM_017948) Human Over-expression Lysate

Human

$960
Cat # LS055035
20 µg, 100 µg

NOL8 Overview

Facts about Nucleolar protein 8.

NOL8 3D structure. Source: alphafold

Nucleolar protein 8 (NOL8)

Plays an essential role in the survival of diffuse-type pancreatic cancer cells. Acts as a nucleolar anchoring protein for DDX47.

May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. .

Gene Information

Human
Gene Name:	NOL8
Uniprot:	Q76FK4
Entrez:	55035

Family

Belongs to:

No superfamily

Alternative Names

NOP132; nucleolar protein 8

Molecular Weight

Mass (kDA):
131.616 kDA

Genomic Context


Human

Location:	9q22.31
Sequence:	9; NC_000009.12 (92297358..92325994, complement)

Tissue Specificity

Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.

Subcellular Localizations

Nucleus, nucleolus. Localizes in the nucleolar-organizing region during ribosome biogenesis.

Diseases

Stomach Neoplasms
Malignant Neoplasm Of Stomach
Becker Muscular Dystrophy
Malignant Neoplasms
Muscular Dystrophy, Duchenne
Dystrophy
Muscular Dystrophy

Carcinogenesis

Pathways

Localization
Ribosome Biogenesis
Cell Cycle
Cell Growth
Rna Interference

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOL8

References

PMID: 15132771 by Jinawath N., et al. Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.

PMID: 14660641 by Sekiguchi T., et al. A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.