OTC Antibodies

AND OTC ELISA kits, OTC Proteins

Many biological assays use antibodies to detect OTC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with OTC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop OTC antibodies...

We validate the specificity of these antibodies to OTC by testing them on tissues known to express OTC positively and negatively. Browse below to find the OTC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for OTC? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the OTC IHC Guide

OTC Infographic by Boster Bio

All OTC Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Ornithine Carbamoyltransferase/OTC Antibody Picoband®

Western blot analysis of OTC using anti-OTC antibody (A00721-1)

Human, Mouse, Rat

$370
Cat # A00721-1
100 μg/vial

Anti-OTC Antibody (Center)

Formalin-fixed and paraffin-embedded human hepatoarcinoma with OTC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining

Flow cytometric analysis of ATDC5 cells using OTC Antibody (Center)(bottom histogram) compared to a negative control (top histogram)

Human, Mouse, Rat

Flow Cytometry, IHC-P, WB

$299
Cat # A00721-2
80 µl

Ornithine Carbamoyltransferase (OTC) (NM_000531) Human Over-expression Lysate

Human

$611
Cat # LS005009
100 µg

Human Ornithine Carbamoyltransferase/OTC Recombinant Protein

SDS-PAGE

$265
Cat # PROTP00480
Starting from 10ug

OTC Overview

Facts about Ornithine carbamoyltransferase, mitochondrial.

OTC 3D structure. Source: alphafold

Ornithine carbamoyltransferase, mitochondrial (OTC)

Gene Information

Human
Gene Name:	OTC
Uniprot:	P00480
Entrez:	5009

Family

Belongs to:

aspartate/ornithine carbamoyltransferase superfamily

Alternative Names

EC 2.1.3; EC 2.1.3.3; MGC129967; MGC129968; MGC138856; OCTD; Ornithine Carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine Transcarbamylase; OTC; OTCase

Molecular Weight

Mass (kDA):
39.935 kDA

Genomic Context


Human

Location:	Xp11.4
Sequence:	X; NC_000023.11 (38352528..38421446)

Tissue Specificity

Mainly expressed in liver and intestinal mucosa.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Ornithine Carbamoyltransferase Deficiency
Pain
Hyperammonemia
Coughing
Headache
Malignant Neoplasms
Infective Disorder
Substance-related Disorders
Common Cold
Neoplasms
Allergy
Urea Cycle Disorders, Inborn
Comatose

Hypertensive Disease
Respiratory Tract Infections
Hemorrhage
Gastrointestinal Diseases
Depressive Disorder
Asthma
Hiv Infections

Pathways

Urea Cycle
Excretion
Transport
Localization
Pathogenesis
Secretion
Aging
Cell Proliferation
Translation
Coagulation
Fermentation
Cell Growth
Immune Response

Hypersensitivity
Drug Resistance
Cell Death
Sensitization
Lactation
Reflex
Protein Import

PTMs

Oxidation
Cleavage
Carboxylation
Reduction
Phosphorylation
Acylation
Nitration

Deacetylation
Acetylation
Methylation
Demethylation
Deamination
Prenylation
Sulphonation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/OTC

References

PMID: 6372096 by Horwich A.L., et al. Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.

PMID: 2836378 by Hata A., et al. Structure of the human ornithine transcarbamylase gene.