Otub2 Antibodies

AND Otub2 ELISA kits, Otub2 Proteins

Many biological assays use antibodies to detect Otub2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Otub2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Otub2 antibodies...

We validate the specificity of these antibodies to Otub2 by testing them on tissues known to express Otub2 positively and negatively. Browse below to find the Otub2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Otub2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the OTUB2 IHC Guide

Otub2 Infographic by Boster Bio

All Otub2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Ubiquitin thioesterase OTUB2 OTUB2 Antibody

Western Blot analysis of various cells using OTUB2 Polyclonal Antibody diluted at 1:2000

Western blot analysis of lysates from COLO, HepG2, Jurkat, 293, and HT-29 cells, using OTUB2 Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A10542-1
100ul

Anti-Ubiquitin thioesterase OTUB2 OTUB2 Antibody

Western blot (WB) analysis of OTUB2 polyclonal antibody at 1:500 dilution
Lane1:HepG2 whole cell lysate(40ug)
Lane2:SGC7901 whole cell lysate(40ug)
Lane3:AML-12 whole cell lysate(40ug)
Lane4:H9C2 whole cell lysate(40ug)

Human, Mouse, Rat

$405
Cat # A10542
100ul

OTUB2 (NM_023112) Human Over-expression Lysate

Human

$628
Cat # LS078990
20 µg, 100 µg

OTUB2 (NM_023112) Human Recombinant Protein

Coomassie blue staining of purified OTUB2 protein

$1249
Cat # PROTQ96DC9
20 µg

Otub2 Overview

Facts about Ubiquitin thioesterase OTUB2.

Ubiquitin thioesterase OTUB2 (Otub2)

Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role in the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'- linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains (By similarity).

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Gene Information

Mouse
Gene Name:	Otub2
Uniprot:	Q9CQX0
Entrez:	68149

Family

Belongs to:

peptidase C65 family

Alternative Names

C14orf137; C14orf137chromosome 14 open reading frame 137; Deubiquitinating enzyme OTUB2; EC 3.4.19.12; FLJ21916; MGC3102; OTB2otubain-2; OTU domain, ubiquitin aldehyde binding 2; OTU domain-containing ubiquitin aldehyde-binding protein 2; OTU2; OTU2ubiquitin thioesterase OTUB2; OTUB2; Otubain2; Otubain-2; ubiquitin-specific protease otubain 2; Ubiquitin-specific-processing protease OTUB2

Molecular Weight

Mass (kDA):
27.3 kDA

Genomic Context


Mouse

Location:	12\|12 E
Sequence:	12;

Diseases

Neoplasms
Ovarian Neoplasm
Sclerosis
Primary Lateral Sclerosis
Nerve Degeneration
Dementia
Postmortem Changes
Hereditary Motor Neurone Disease
Malignant Paraganglionic Neoplasm

Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Feline Urological Syndrome
Liposarcoma

Pathways

Cell Cycle
Rna Processing
Localization

PTMs

Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Otub2

References

PMID: 16141072 by Carninci P., et al. The transcriptional landscape of the mammalian genome.

PMID: 21183079 by Huttlin E.L., et al. A tissue-specific atlas of mouse protein phosphorylation and expression.