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- Table of Contents
PAH Antibodies
AND PAH ELISA kits, PAH Proteins
Many biological assays use antibodies to detect PAH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAH antibodies...
Designing a Western blot for PAH? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PAH Western Blot GuidePAH Infographic by Boster Bio
All PAH Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00761-1
100 μg/vial
Cat # A00761-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00761
100 μl/vial
Cat # M00761
100 μl/vial
PAH Overview
Facts about Phenylalanine-4-hydroxylase.
Phenylalanine-4-hydroxylase (PAH)
Catalyzes the hydroxylation of L-phenylalanine to L- tyrosine.
.Gene Information
| Human | |
|---|---|
| Gene Name: | PAH |
| Uniprot: | P00439 |
| Entrez: | 5053 |
Family
| Belongs to: |
|---|
| biopterin-dependent aromatic amino acid hydroxylase family |
Alternative Names
EC 1.14.16; EC 1.14.16.1; PH; phe-4-monooxygenase; phenylalanine 4-monooxygenase; phenylalanine hydroxylase; phenylalanine-4-hydroxylase; PKU; PKU1
Molecular Weight
Mass (kDA):
51.862 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q23.2 |
| Sequence: | 12; NC_000012.12 (102836889..102958441, complement) |
Diseases
- Hypertensive Disease
- Idiopathic Pulmonary Hypertension
- Pulmonary Hypertension
- Malignant Neoplasms
- Phenylketonurias
- Neoplasms
- Carcinogenesis
- Malignant Neoplasm Of Lung
- Hyperphenylalaninemia
- Kidney Diseases
- Lung Neoplasms
Pathways
- Transport
- Excretion
- Glomerular Filtration
- Secretion
- Pathogenesis
- Anion Transport
- Organic Anion Transport
- Diuresis
- Vasoconstriction
- Cell Proliferation
- Natriuresis
- Dna Repair
- Localization
PTMs
- Oxidation
- Hydroxylation
- Nitration
- Phosphorylation
- Methylation
- Carboxylation
- Cleavage
- Reduction
- Acetylation
- Bromination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAH
bosterbio.com/bosterbio-gene-info-cards/PAH
References
PMID: 2986678 by Kwok S.C.M., et al. Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase.
PMID: 2461704 by Cotton R.G., et al. A monoclonal antibody to aromatic amino acid hydroxylases. Identification of the epitope.
2 Publications of Boster PAH Antibodies & ELISA Kits
- PubMed ID: 10.1038/s41598-021-86663-8, CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as...
- PubMed ID: 33790381, Singh K,Cornell CS,Jackson R,Kabiri M,Phipps M,Desai M,Fogle R,Ying X,Anarat-Cap...
*More publications can be found for each product on its corresponding product page