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Paired box protein Pax-2 Antibodies
AND PAX2 ELISA kits, Paired box protein Pax-2 Proteins
Many biological assays use antibodies to detect Paired box protein Pax-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-2 antibodies...
Designing an IHC experiment for Paired box protein Pax-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PAX2 IHC GuidePAX2 Infographic by Boster Bio
All PAX2 Products
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Specificity
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PAX2 Overview
Facts about Paired box protein Pax-2.
Paired box protein Pax-2 (PAX2)
Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
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Gene Information
| Human | |
|---|---|
| Gene Name: | PAX2 |
| Uniprot: | Q02962 |
| Entrez: | 5076 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
paired box 2; paired box gene 2; paired box homeotic gene 2; paired box protein Pax-2; Pax2
Molecular Weight
Mass (kDA):
44.706 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q24.31 |
| Sequence: | 10; NC_000010.11 (100735396..100829944) |
Tissue Specificity
Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Congenital Ocular Coloboma (disorder)
- Carcinoma
- Nervousness
- Kidney Diseases
- Malignant Neoplasms
- Nephroblastoma
- Kidney Neoplasm
- Renal Cell Carcinoma
- Hypoplasia
- Renal Coloboma Syndrome
- Congenital Abnormality
- Kidney Failure
Pathways
- Kidney Development
- Cell Proliferation
- Eye Development
- Cell Death
- Pathogenesis
- Regionalization
- Gastrulation
- Localization
- Cell Differentiation
- Ear Development
- Cell Growth
- Regeneration
- Cell Cycle
PTMs
- Phosphorylation
- Methylation
- Cleavage
Research Areas
- Neuronal Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX2
bosterbio.com/bosterbio-gene-info-cards/PAX2
References
PMID: 1378753 by Eccles M.R., et al. Expression of the PAX2 gene in human fetal kidney and Wilms' tumor.
PMID: 7819127 by Ward T.A., et al. Alternative messenger RNA forms and open reading frames within an additional conserved region of the human PAX-2 gene.
2 Publications of Boster Paired box protein Pax-2 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.bbr.2020.112803, Increased repetitive self-grooming occurs in Pax2 mutant mice generated using CR...
- PubMed ID: 29138573, Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-...
*More publications can be found for each product on its corresponding product page