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Paired box protein Pax-8 Antibodies
AND PAX8 ELISA kits, Paired box protein Pax-8 Proteins
Many biological assays use antibodies to detect Paired box protein Pax-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paired box protein Pax-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paired box protein Pax-8 antibodies...
Designing a Western blot for Paired box protein Pax-8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PAX8 Western Blot GuidePAX8 Infographic by Boster Bio
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PAX8 Overview
Facts about Paired box protein Pax-8.
Paired box protein Pax-8 (PAX8)
Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, keeping the functional differentiation of such cells. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PAX8 |
| Uniprot: | Q06710 |
| Entrez: | 7849 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8
Molecular Weight
Mass (kDA):
48.218 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q14.1 |
| Sequence: | 2; NC_000002.12 (113215997..113278921, complement) |
Tissue Specificity
Expressed in the excretory system, thyroid gland and Wilms tumors.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Carcinoma
- Thyroid Neoplasm
- Malignant Neoplasms
- Malignant Neoplasm Of Thyroid
- Hypothyroidism
- Congenital Hypothyroidism
- Follicular Thyroid Carcinoma
- Carcinoma, Papillary
- Adenoma
- Congenital Abnormality
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- NCL
- SERINC1
Pathways
- Pathogenesis
- Cell Proliferation
- Kidney Development
- Cell Differentiation
- Cell Growth
- Localization
- Gland Development
- Ear Development
- Translation
- Gastrulation
- Dedifferentiation
- Cell Cycle
- Thyroid Gland Development
PTMs
- Phosphorylation
- Methylation
- Reduction
- Glutathionylation
- Acetylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAX8
bosterbio.com/bosterbio-gene-info-cards/PAX8
References
PMID: 1337742 by Poleev A., et al. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors.
PMID: 8413205 by Kozmik Z., et al. Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.