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- Table of Contents
PDE6A Antibodies
AND PDE6A ELISA kits, PDE6A Proteins
Many biological assays use antibodies to detect PDE6A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE6A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE6A antibodies...
Designing a Western blot for PDE6A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PDE6A Western Blot GuideDesigning an IHC experiment for PDE6A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PDE6A IHC GuidePDE6A Infographic by Boster Bio
All PDE6A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07800-1
100 μg/vial
Cat # A07800-1
100 μg/vial
PDE6A Overview
Facts about Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha.
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (PDE6A)
This protein participates in processes of transmission and amplification of the visual signal. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PDE6A |
| Uniprot: | P16499 |
| Entrez: | 5145 |
Family
| Belongs to: |
|---|
| cyclic nucleotide phosphodiesterase family |
Alternative Names
CGPR-A; EC 3.1.4; EC 3.1.4.35; GMP-PDE alpha; PDE V-B1; PDEAcGMP phosphodiesterase alpha subunit; phosphodiesterase 6A, cGMP-specific, rod, alpha; rod cGMP-specific 3'-5'-cyclic phosphodiesterase subunit alpha; rod photoreceptor cGMP phosphodiesterase alpha subunit; RP43
Molecular Weight
Mass (kDA):
99.547 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q32 |
| Sequence: | 5; NC_000005.10 (149857953..149944793, complement) |
Subcellular Localizations
Cell membrane; Lipid-anchor; Cytoplasmic side.
Diseases
- Retinitis Pigmentosa
- Retinal Degeneration
- Dog Diseases
- Atrophy
- Atrophic Retina
- Blind Vision
- Dysplasia
- Retinal Diseases
- Retinal Dystrophies
- Amaurosis
- Macular Edema, Cystoid
- Edema
Pathways
- Phototransduction
- Pathogenesis
- Hypersensitivity
- Reflex
PTMs
- Acetylation
- Lipoprotein
Research Areas
- Signal Transduction
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE6A
bosterbio.com/bosterbio-gene-info-cards/PDE6A
References
PMID: 2155175 by Pittler S.J., et al. Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase alpha-subunit and chromosomal localization of the human gene.
PMID: 7493036 by Huang S.H., et al. Autosomal recessive retinitis pigmentosa caused by mutations in the alpha subunit of rod cGMP phosphodiesterase.