PDHB Antibodies

AND PDHB ELISA kits, PDHB Proteins

Many biological assays use antibodies to detect PDHB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDHB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDHB antibodies...

We validate the specificity of these antibodies to PDHB by testing them on tissues known to express PDHB positively and negatively. Browse below to find the PDHB antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDHB Infographic by Boster Bio

All PDHB Products

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Anti-Pyruvate Dehydrogenase E1 beta subunit PDHB Monoclonal Antibody

4 Q&As

Western blot analysis of PDHB using anti-PDHB antibody (M03998)

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M03998
100 μl

Anti-PDHB Antibody

Western blot analysis of extracts of various cell lines, using PDHB antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A03998
100ul

Anti-PDHB Antibody

Western blot analysis of Pyruvate Dehydrogenase E1 beta subunit on HepG2 (1) and Hela (2) cell lysate using anti-Pyruvate Dehydrogenase E1 beta subunit antibody at 1/1,000 dilution

Western blot analysis of Pyruvate Dehydrogenase E1 beta subunit on mouse kidney tissue (1) and PC-12 (2) cell lysate using anti-Pyruvate Dehydrogenase E1 beta subunit antibody at 1/1,000 dilution

Human, Mouse, Rat

Flow Cytometry, IP, IHC, WB

$405
Cat # A03998-1
100ul

Anti-PDHB Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A03998-2
100 μl/vial

PDHB Overview

Facts about Pyruvate dehydrogenase E1 component subunit beta, mitochondrial.

PDHB 3D structure. Source: alphafold

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB)

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. .

Gene Information

Human
Gene Name:	PDHB
Uniprot:	P11177
Entrez:	5162

Family

Belongs to:

No superfamily

Alternative Names

DKFZp564K0164; mitochondrial; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase, E1 beta polypeptide

Molecular Weight

Mass (kDA):
39.233 kDA

Genomic Context


Human

Location:	3p14.3
Sequence:	3; NC_000003.12 (58427630..58433852, complement)

Subcellular Localizations

Mitochondrion matrix.

Diseases

Acidosis
Acidosis, Lactic
Pyruvate Dehydrogenase Complex Deficiency Disease
Ataxia
Malignant Neoplasms
Neoplasms
Congenital Absence
Muscle Hypotonia
Neurodegenerative Disorders
Parkinson Disease
Stomach Neoplasms

Malnutrition
Melanoma
Mitochondrial Diseases
Carcinoma
Immunologic Deficiency Syndromes

Interacting Proteins

DLAT
PDHA1

Pathways

Cell Migration
Nitrogen Fixation
Pathogenesis
Glycolysis
Pyruvate Oxidation
Photosynthesis
Brain Development
Fertilization
Regulation Of Sporulation
Oxidative Phosphorylation
Membrane Fusion
Virulence
Sporulation

Conjugation
Localization
Fermentation
Translation
Acrosome Reaction
Sperm Capacitation
Cell Growth

PTMs

Phosphorylation
Oxidation
Carboxylation

Decarboxylation
Acetylation
Ribosylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDHB

References

PMID: 2323578 by Ho L., et al. Cloning and cDNA sequence of the beta-subunit component of human pyruvate dehydrogenase complex.

PMID: 1702713 by Chun K., et al. Isolation, characterization and chromosomal localization of cDNA clones for the E1 beta subunit of the pyruvate dehydrogenase complex.