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- Table of Contents
PDLIM7 Antibodies
AND PDLIM7 ELISA kits, PDLIM7 Proteins
Many biological assays use antibodies to detect PDLIM7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDLIM7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDLIM7 antibodies...
Designing a Western blot for PDLIM7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PDLIM7 Western Blot GuideDesigning an IHC experiment for PDLIM7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PDLIM7 IHC GuidePDLIM7 Infographic by Boster Bio
All PDLIM7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04377-1
100 μg/vial
Cat # A04377-1
100 μg/vial
PDLIM7 Overview
Facts about PDZ and LIM domain protein 7.
PDZ and LIM domain protein 7 (PDLIM7)
May serve as a scaffold where the coordinated assembly of proteins may occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues.
Involved in both of those two basic mechanisms of bone formation, direct bone formation (e.g.
Gene Information
| Human | |
|---|---|
| Gene Name: | PDLIM7 |
| Uniprot: | Q9NR12 |
| Entrez: | 9260 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
1110003B01Rik; ENIGMAProtein enigma; LIM domain protein; LIM mineralization protein; LMP; LMP1; PDZ and LIM domain 7 (enigma); PDZ and LIM domain protein 7
Molecular Weight
Mass (kDA):
49.845 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q35.3 |
| Sequence: | 5; NC_000005.10 (177483394..177497605, complement) |
Tissue Specificity
Isoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver.
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity).
Diseases
- Neoplasms
- Carcinoma
- Lymphoma
- Malignant Neoplasms
- Nasopharyngeal Neoplasms
- Epstein-barr Virus Infections
- Cancer Of Nasopharynx
- Hodgkin Disease
- Burkitt Lymphoma
- Malignant Squamous Cell Neoplasm
- Malignant Paraganglionic Neoplasm
- Skin Neoplasms
- T-cell Lymphoma
Interacting Proteins
- BAG3
- ENKD1
- GEM
- Hoxa1
- PHF1
- TSG101
- UBQLN4
- WWP2
Pathways
- Osteoblast Differentiation
- Localization
- Pathogenesis
- Cell Proliferation
- Transport
- Immune Response
- Cytoskeleton Organization
- Odontoblast Differentiation
- Regeneration
- Cell Differentiation
- Actin Cytoskeleton Organization
- Secretion
- Cell Activation
PTMs
- Phosphorylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDLIM7
bosterbio.com/bosterbio-gene-info-cards/PDLIM7
References
PMID: 7929196 by Wu R.-Y., et al. LIM domain recognition of a tyrosine-containing tight turn.
PMID: 11874232 by Liu Y., et al. Overexpressed LIM mineralization proteins do not require LIM domains to induce bone.