Pyridoxal kinase Antibodies

AND PDXK ELISA kits, Pyridoxal kinase Proteins

Many biological assays use antibodies to detect Pyridoxal kinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pyridoxal kinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pyridoxal kinase antibodies...

We validate the specificity of these antibodies to Pyridoxal kinase by testing them on tissues known to express PDXK positively and negatively. Browse below to find the PDXK antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Pyridoxal kinase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PDXK IHC Guide

PDXK Infographic by Boster Bio

All PDXK Products

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Product

Figures

Specificity

Applications

Price

Anti-PDXK Antibody Picoband®

Western blot analysis of PDXK using anti-PDXK antibody (A06683-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06683-1
100 µg/vial

Anti-PDXK Antibody (N-term)

Human

IHC-P, WB

$299
Cat # M06683
50 µl

PDXK (NM_003681) Human Over-expression Lysate

Human

$628
Cat # LS008566
20 µg, 100 µg

Human Pyridoxal Kinase/PDXK Recombinant Protein

SDS-PAGE

$265
Cat # PROTO00764
Starting from 10ug

PDXK Overview

Facts about Pyridoxal kinase.

PDXK 3D structure. Source: alphafold

Pyridoxal kinase (PDXK)

Required for synthesis of pyridoxal-5-phosphate from vitamin B6. .

Gene Information

Human
Gene Name:	PDXK
Uniprot:	O00764
Entrez:	8566

Family

Belongs to:

pyridoxine kinase family

Alternative Names

C21orf124; C21orf97; chromosome 21 open reading frame 124; DKFZp566A071; EC 2.7.1.35; FLJ21324; FLJ37311; HEL-S-1a; MGC15873; MGC31754; MGC52346; PDXK; PKH; PKHchromosome 21 open reading frame 97; PNK; PNKhuman pyridoxal kinase, EC 2.7.1.3510FLJ31940; PRED79; pyridoxal (pyridoxine, vitamin B6) kinase; Pyridoxal Kinase; pyridoxamine kinase; Pyridoxine kinase; Vitamin B6 Kinase

Molecular Weight

Mass (kDA):
35.102 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (43719129..43762299)

Tissue Specificity

Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Down Syndrome
Parkinson Disease
Neurodegenerative Disorders
Malnutrition
Malignant Neoplasm Of Lung
Carcinoma
Carcinogenesis
Neoplasms
Steroid Sulfatase Deficiency Disease
Cytogenetic Abnormality
Colorectal Cancer

Infective Disorder
Influenza
Non-small Cell Lung Carcinoma
Genomic Instability
Tissue Adhesions
Essential Tremor
Epilepsy

Pathways

Transport
Pathogenesis
Vesicle Transport
Posttranscriptional Regulation Of Gene Expression
Axon Guidance
Cell Cycle
Dna Damage Checkpoint
Regulation Of Gene Expression

Excretion
Cell-cell Adhesion

PTMs

Phosphorylation

Carboxylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDXK

References

PMID: 9099727 by Hanna M.C., et al. Human pyridoxal kinase. cDNA cloning, expression, and modulation by ligands of the benzodiazepine receptor.

PMID: 15154080 by Fang X., et al. Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis.