PGRMC1 Antibodies

AND PGRMC1 ELISA kits, PGRMC1 Proteins

Many biological assays use antibodies to detect PGRMC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PGRMC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PGRMC1 antibodies...

We validate the specificity of these antibodies to PGRMC1 by testing them on tissues known to express PGRMC1 positively and negatively. Browse below to find the PGRMC1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PGRMC1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PGRMC1 IHC Guide

PGRMC1 Infographic by Boster Bio

All PGRMC1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PGRMC1 Antibody Picoband®

IHC analysis of PGRMC1 using anti-PGRMC1 antibody (PB9775)

IF analysis of PGRMC1 using anti-PGRMC1 antibody (PB9775)

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # PB9775
100 μg/vial

PGRMC1 (NM_006667) Human Over-expression Lysate

Human

$628
Cat # LS010857
20 µg, 100 µg

PGRMC1 (NM_006667) Human Recombinant Protein

Coomassie blue staining of purified PGRMC1 protein

$1249
Cat # PROTO00264
20 µg

PGRMC1 Overview

Facts about Membrane-associated progesterone receptor component 1.

PGRMC1 3D structure. Source: alphafold

Membrane-associated progesterone receptor component 1 (PGRMC1)

Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345).

Has lots of reported cellular functions (heme homeostasis, interaction with CYPs). .

Gene Information

Human
Gene Name:	PGRMC1
Uniprot:	O00264
Entrez:	10857

Family

Belongs to:

cytochrome b5 family

Alternative Names

HPR6.6; HPR6.6PGRMC; membrane-associated progesterone receptor component 1; MPR; PGRMC1; Progesterone Binding Protein; progesterone receptor membrane component 1

Molecular Weight

Mass (kDA):
21.671 kDA

Genomic Context


Human

Location:	Xq24
Sequence:	X; NC_000023.11 (119236245..119244466)

Tissue Specificity

Widely expressed, with highest expression in liver and kidney.

Subcellular Localizations

Microsome membrane; Single-pass membrane protein. Smooth endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Cell Transformation, Neoplastic
Nervousness
Ovarian Neoplasm
Turner Syndrome
Ovarian Failure, Premature
Premature Menopause
Endometrial Polyp

Carcinoma
Inflammation
Infertility
Traumatic Brain Injury
Brain Injuries
Lung Neoplasms
Hypoxia

Interacting Proteins

FECH
POR

Pathways

Localization
Cell Proliferation
Fertilization
Embryo Development
Methylation
Cell Death
Ovulation
Oocyte Maturation
Regeneration
Acrosome Reaction
Cellular Localization
Neurogenesis
Neuroprotection

Secretion
Insemination
Reproductive Behavior
Transport
Aging
Translation
Cell Cycle

PTMs

Phosphorylation
Methylation
Sumoylation

Cleavage
Biotinylation
Acetylation

Oxidation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGRMC1

References

PMID: 9705155 by Gerdes D., et al. Cloning and tissue expression of two putative steroid membrane receptors.

PMID: 11697142 by Bernauer S., et al. The human membrane progesterone receptor gene: genomic structure and promoter analysis.