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- Table of Contents
Facts about GPI ethanolamine phosphate transferase 1.
May act as suppressor of replication stress and chromosome missegregation. .
Human | |
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Gene Name: | PIGN |
Uniprot: | O95427 |
Entrez: | 23556 |
Belongs to: |
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PIGG/PIGN/PIGO family |
EC 2.-; GPI ethanolamine phosphate transferase 1; MCD4 homolog; MCD4; MDC4; MGC26427; phosphatidylinositol glycan anchor biosynthesis, class N; Phosphatidylinositol-glycan biosynthesis class N protein; PIG-Nphosphatidylinositol glycan, class N
Mass (kDA):
105.81 kDA
Human | |
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Location: | 18q21.33 |
Sequence: | 18; NC_000018.10 (62041164..62187118, complement) |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
PMID: 10069808 by Gaynor E.C., et al. MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast.
PMID: 23446422 by Burrell R.A., et al. Replication stress links structural and numerical cancer chromosomal instability.