Perilipin-5 Antibodies

AND Plin5 ELISA kits, Perilipin-5 Proteins

Many biological assays use antibodies to detect Perilipin-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Perilipin-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Perilipin-5 antibodies...

We validate the specificity of these antibodies to Perilipin-5 by testing them on tissues known to express Plin5 positively and negatively. Browse below to find the Plin5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Perilipin-5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PLIN5 Western Blot Guide

Plin5 Infographic by Boster Bio

All Plin5 Products

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Anti-PLIN5 Antibody Picoband®

Western blot analysis of PLIN5 using anti-PLIN5 antibody (A05479-1)

IHC analysis of PLIN5 using anti-PLIN5 antibody (A05479-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A05479-1
100 μg/vial

LSDP5 (PLIN5) (NM_001013706) Human Over-expression Lysate

Human

$628
Cat # LS440503
20 µg, 100 µg

Plin5 Overview

Facts about Perilipin-5.

Perilipin-5 (Plin5)

Lipid droplet-associated protein that keeps the equilibrium between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by controlling both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation.

In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three important key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduce the triacylglycerol hydrolase activity of PNPLA2 by recruitment and sequestering PNPLA2 to lipid droplets.

Gene Information

Mouse
Gene Name:	Plin5
Uniprot:	Q8BVZ1
Entrez:	66968

Family

Belongs to:

perilipin family

Alternative Names

lipid storage droplet protein 5; LSDA5; LSDP5; MLDP; OXPAT; perilipin 5; perilipin-5

Molecular Weight

Mass (kDA):
50.474 kDA

Genomic Context


Mouse

Location:	17\|17 D
Sequence:	17;

Tissue Specificity

Highly expressed in oxidative tissues, including heart, liver, brown adipose tissue (BAT) and slow-twitch fibers of skeletal muscle. Lower expression in epididymal white adipose tissue and anterior tibialis and quadriceps. Expressed in adrenal glands. Isoform 2 has the highest expression in heart.

Diseases

Obesity
Dysequilibrium Syndrome
Metabolic Syndrome X
Liver Diseases
Steatohepatitis
Atherosclerosis
Diabetes Mellitus
Coronary Artery Disease
Steatosis

Physiological Stress
Insulin Resistance
Cardiomyopathies
Fatty Liver

Pathways

Lipid Homeostasis
Lipid Storage
Fatty Acid Oxidation
Localization

PTMs

Oxidation

Research Areas

Diabetes Research
Lipid and Metabolism
Lipid Droplets

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Plin5

References

PMID: 17234449 by Dalen K.T., et al. LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues.

PMID: 17130488 by Wolins N.E., et al. OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization.