POMT2 Antibodies

AND POMT2 ELISA kits, POMT2 Proteins

Many biological assays use antibodies to detect POMT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POMT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POMT2 antibodies...

We validate the specificity of these antibodies to POMT2 by testing them on tissues known to express POMT2 positively and negatively. Browse below to find the POMT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POMT2 Infographic by Boster Bio

All POMT2 Products

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Anti-POMT2 Antibody Picoband®

13 Q&As

Western blot analysis of POMT2 using anti-POMT2 antibody (A04876-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04876-1
100 μg/vial

POMT2 (NM_013382) Human Over-expression Lysate

Human

$628
Cat # LS029954
20 µg, 100 µg

POMT2 Overview

Facts about Protein O-mannosyl-transferase 2.

POMT2 3D structure. Source: alphafold

Protein O-mannosyl-transferase 2 (POMT2)

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.

Gene Information

Human
Gene Name:	POMT2
Uniprot:	Q9UKY4
Entrez:	29954

Family

Belongs to:

glycosyltransferase 39 family

Alternative Names

DKFZp686G10254; Dolichyl-phosphate-mannose--protein mannosyltransferase 2; EC 2.4.1.109; FLJ22309; MDDGA2; MDDGB2; MDDGC2; protein O-mannosyl-transferase 2; protein-O-mannosyltransferase 2

Molecular Weight

Mass (kDA):
84.214 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (77274956..77320885, complement)

Tissue Specificity

Highly expressed in testis; detected at low levels in most tissues.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Muscular Dystrophy
Dystrophy
Walker-warburg Congenital Muscular Dystrophy
Congenital Muscular Dystrophy (disorder)
Coronary Microvascular Disease
Muscle Eye Brain Disease
Congenital Anomaly Of Brain
Lissencephaly
Eye Abnormalities
Fukuyama Type Congenital Muscular Dystrophy
Hypoplasia
Weakness

Muscular Dystrophies, Limb-girdle
Hydrocephalus
Nervousness
Alpha-dystroglycanopathies
Microcephaly
Muscle Weakness
Cobblestone Lissencephaly

Pathways

Glycosylation
Rna Interference
Localization
Dentate Gyrus Development
Eye Pigmentation
Brain Development
Aging
Fertilization
Muscle Contraction
Pigmentation
Embryo Development
Flight

Eclosion
Mrna Splicing
Muscle Attachment
Neuron Migration
Locomotion
Rna Processing
Pathogenesis

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMT2

References

PMID: 12460945 by Willer T., et al. Characterization of POMT2, a novel member of the PMT protein O- mannosyltransferase family specifically localized to the acrosome of mammalian spermatids.

PMID: 14699049 by Manya H., et al. Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity.