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- Table of Contents
PON2 Antibodies
AND PON2 ELISA kits, PON2 Proteins
Many biological assays use antibodies to detect PON2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PON2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PON2 antibodies...
Designing a Western blot for PON2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PON2 Western Blot GuideDesigning an IHC experiment for PON2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PON2 IHC GuidePON2 Infographic by Boster Bio
All PON2 Products
Product
Figures
Specificity
Applications
Price
PON2 Overview
Facts about Serum paraoxonase/arylesterase 2.
Serum paraoxonase/arylesterase 2 (PON2)
Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity.
Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Gene Information
| Human | |
|---|---|
| Gene Name: | PON2 |
| Uniprot: | Q15165 |
| Entrez: | 5445 |
Family
| Belongs to: |
|---|
| paraoxonase family |
Alternative Names
A-esterase 2; Aromatic esterase 2; EC 3.1.1.2; EC 3.1.1.81; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum Aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
Molecular Weight
Mass (kDA):
39.381 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.3 |
| Sequence: | 7; NC_000007.14 (95404862..95435072, complement) |
Tissue Specificity
Widely expressed with highest expression in liver, lung, placenta, testis and heart.
Subcellular Localizations
Membrane; Peripheral membrane protein.
Diseases
- Atherosclerosis
- Diabetes Mellitus
- Cardiovascular Diseases
- Coronary Heart Disease
- Diabetes Mellitus, Non-insulin-dependent
- Heart Diseases
- Coronary Artery Disease
- Arteriosclerosis
- Dysequilibrium Syndrome
- Cerebrovascular Accident
- Inflammation
- Cholangiocarcinoma
Pathways
- Pathogenesis
- Quorum Sensing
- Virulence
- Aging
- Localization
- Cholesterol Efflux
- Cell Death
- Secretion
- Transport
- Inflammatory Response
- Lipoprotein Oxidation
- Biofilm Formation
- Glomerular Filtration
PTMs
- Oxidation
- Phosphorylation
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PON2
bosterbio.com/bosterbio-gene-info-cards/PON2
References
PMID: 8661009 by Primo-Parmo S.L., et al. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
PMID: 9714608 by Mochizuki H., et al. Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.