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- Table of Contents
POU2AF1 Antibodies
AND POU2AF1 ELISA kits, POU2AF1 Proteins
Many biological assays use antibodies to detect POU2AF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU2AF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU2AF1 antibodies...
Designing an IHC experiment for POU2AF1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the POU2AF1 IHC GuidePOU2AF1 Infographic by Boster Bio
All POU2AF1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04431-3
100 μl/vial
Cat # M04431-3
100 μl/vial
POU2AF1 Overview
Facts about POU domain class 2-associating factor 1.
POU domain class 2-associating factor 1 (POU2AF1)
Transcriptional coactivator that specifically associates with OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2.
It has no intrinsic DNA-binding activity. It admits the POU domains of OCT1 and OCT2.
Gene Information
| Human | |
|---|---|
| Gene Name: | POU2AF1 |
| Uniprot: | Q16633 |
| Entrez: | 5450 |
Family
| Belongs to: |
|---|
| POU2AF1 family |
Alternative Names
B-cell-specific coactivator OBF-1; BOB-1; OBF-1; OBF1BOB1; OCAB; OCA-B; OCT-binding factor 1; POU class 2 associating factor 1; POU domain class 2, associating factor 1; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1
Molecular Weight
Mass (kDA):
27.436 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q23.1 |
| Sequence: | 11; NC_000011.10 (111352251..111379671, complement) |
Tissue Specificity
B-cell specific.
Subcellular Localizations
Nucleus.
Diseases
- Lymphoma
- Hodgkin Disease
- B-cell Lymphomas
- Neoplasms
- Classical Hodgkin's Lymphoma
- Diffuse Large B-cell Lymphoma
- Leukemia
- Nodular Lymphocyte Predominant Hodgkin Lymphoma
- Lymphoma, Non-hodgkin
- Malignant Neoplasms
- Chromosomal Translocation
- Plasmacytoma
- Ki-1+ Anaplastic Large Cell Lymphoma
Interacting Proteins
- SIAH1
Pathways
- Cell Development
- Germinal Center Formation
- Cell Differentiation
- B Cell Differentiation
- Immune Response
- Cell Maturation
- Pathogenesis
- Cell Activation
- B Cell Activation
- Immunoglobulin Production
- Localization
- Secretion
- Cell Cycle
PTMs
- Phosphorylation
- Myristoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU2AF1
bosterbio.com/bosterbio-gene-info-cards/POU2AF1
References
PMID: 7859290 by Strubin M., et al. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer- binding proteins.
PMID: 7779176 by Gstaiger M., et al. A B-cell coactivator of octamer-binding transcription factors.