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PPARG Antibodies
AND PPARG ELISA kits, PPARG Proteins
Many biological assays use antibodies to detect PPARG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPARG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPARG antibodies...
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PPARG Infographic by Boster Bio
All PPARG Products
Product
Figures
Specificity
Applications
Price
Anti-PPAR gamma/PPARG Antibody Picoband™
20 Citations 16 Q&As
Human
WB
$370
Cat # A00449-2
100 μg/vial
Cat # A00449-2
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1482
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1482
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2111
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2111
1 kit, containing two 96-well plates and all necessary reagents
Anti-PPAR gamma/PPARG Antibody Picoband™
3 Citations
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00449-3
100 μg/vial
Cat # A00449-3
100 μg/vial
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M00449-2
100 µl/vial
Cat # M00449-2
100 µl/vial
PPARG Overview
Facts about Peroxisome proliferator-activated receptor gamma.
Peroxisome proliferator-activated receptor gamma (PPARG)
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.
It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.
Gene Information
| Human | |
|---|---|
| Gene Name: | PPARG |
| Uniprot: | P37231 |
| Entrez: | 5468 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
CIMT1; NR1C3; NR1C3GLM1; Nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor gamma; PPAR gamma; PPARG; PPARG1peroxisome proliferative activated receptor, gamma; PPARG2PPARgamma; PPAR-gamma
Molecular Weight
Mass (kDA):
57.62 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.2 |
| Sequence: | 3; NC_000003.12 (12287485..12434344) |
Tissue Specificity
Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary.
Subcellular Localizations
Nucleus. Cytoplasm. Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Insulin Resistance
- Malignant Neoplasms
- Inflammation
- Insulin Sensitivity
- Neoplasms
- Lipodystrophy
- Acquired Partial Lipodystrophy
- Cardiovascular Diseases
- Hypertensive Disease
- Familial Partial Lipodystrophy
Interacting Proteins
- CDK5
- CLU
- EDF1
- HTT
- NR1H3
- PPARGC1A
- RXRA
- SIRT1
Pathways
- Secretion
- Pathogenesis
- Insulin Secretion
- Cell Cycle
- Cell Proliferation
- Cell Differentiation
- Glucose Homeostasis
- Methylation
- Transport
- Tissue Development
- Dna Methylation
- Translation
- Aging
PTMs
- Phosphorylation
- Methylation
- Oxidation
- Deacetylation
Research Areas
- Cancer
- mTOR Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPARG
bosterbio.com/bosterbio-gene-info-cards/PPARG
Boster Bio - Best Uses Of The PPARG Marker
When you have been looking for information about the PPARG marker, you have probably already come across the company's signature ELISA products. However, you may not have realized that Boster Bio is now providing PCR-related molecular biology products. Depending on your needs, they can offer various services, such as free technical resources, technical support, and more. Let's take a closer look at how they can help you.
Phytanic acid
The PPARG gene encodes a protein that is expressed in the body and plays an important role in many processes. Scientists can identify and use PPARG to determine their metabolic rate and target fat. However, there are many factors that contribute to its inhibition. Fortunately, there are several natural ligands for PPARg. These compounds have a number of positive effects on the body, including increasing glucose uptake and insulin sensitivity.
PPARg is a ligand-binding protein with a cavity that is three to four times larger than the one in other nuclear receptors. These natural ligands can bind to the receptors and regulate the expression of target genes. These ligands have been shown to inhibit tumor development through activation of PPARg. Some eicosanoids are natural ligands of PPARg. Prostaglandin PGJ2 and leukotriene B4 stimulate PPARa and PPARg.
References
PMID: 9065481 by Mukherjee R., et al. Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists.
PMID: 8702406 by Elbrecht A., et al. Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2.
26 Publications of Boster PPARG Antibodies & ELISA Kits
- PubMed ID: 10.4314/tjpr.v16i11.13, Prophylactic effects of triptolide on colon cancer development in azoxymethane/d...
- PubMed ID: 10.4161/rna.8.5.16043, MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by...
- PubMed ID: 10.3892/etm.2011.208, Enhanced peroxisomal β-oxidation metabolism in visceral adipose tissues of high...
- PubMed ID: 10.3390/ani11123468, Effect of Actin Alpha Cardiac Muscle 1 on the Proliferation and Differentiation ...
- PubMed ID: 10.3389/fphys.2021.707344, Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-...
- PubMed ID: 10.1371/journal.pone.0071265, Electrospun Poly(L-lactide)/Poly(ε-caprolactone) Blend Nanofibrous Scaffold: Ch...
- PubMed ID: 10.1186/s12883-015-0287-3, Rosiglitazone infusion therapy following minimally invasive surgery for intracer...
- PubMed ID: 10.1093/ecam/neq031, Scorpion in Combination with Gypsum: Novel Antidiabetic Activities in Streptozot...
- PubMed ID: 10.1021/acs.jafc.0c05147, Bovine Stearoyl-CoA Desaturase 1 Promotes Adipogenesis by Activating the PPARγ ...
- PubMed ID: 10.1016/j.febslet.2006.12.043, The effect of pleiotrophin signaling on adipogenesis
- PubMed ID: 10.1016/j.anireprosci.2019.05.006, Effect of maternal feed restriction in dairy goats at different stages of gestat...
- PubMed ID: 10.1007/s11596-017-1698-8, Dietary restriction reduces blood lipids and ameliorates liver function of mice ...
- PubMed ID: 10.1002/bem.21867, The effect of electromagnetic fields on the proliferation and the osteogenic or ...
- PubMed ID: 10.1002/bem.21867, The effect of electromagnetic fields on the proliferation and the osteogenic or ...
- PubMed ID: 10.1002/bem.21867, The effect of electromagnetic fields on the proliferation and the osteogenic or ...
- PubMed ID: 32018039, Chen G,Wang Q,Li Z,Yang Q,Liu Y,Du Z,Zhang G,Song Y.Circular RNA CDR1as promotes...
- PubMed ID: -, Li,A.;Su,X.;Wang,Y.;Cheng,G.;Zan,L.;Wang,H.Effect of Neudesin Neurotrophic Facto...
- PubMed ID: 33321855, Chen X, Raza SHA, Cheng G, Ma X, Wang J, Zan L. Bta-miR-376a Targeting KLF15 Int...
- PubMed ID: 26021445, Rosiglitazone infusion therapy following minimally invasive surgery for intracer...
- PubMed ID: 22977503, Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-...
- PubMed ID: 23990941, Electrospun Poly(L-lactide)/Poly(?-caprolactone) Blend Nanofibrous Scaffold: Cha...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page