This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
PPARGC1B Antibodies
AND PPARGC1B ELISA kits, PPARGC1B Proteins
Many biological assays use antibodies to detect PPARGC1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPARGC1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPARGC1B antibodies...
Previous: Septin9
Next: UGT3A1
PPARGC1B Infographic by Boster Bio
All PPARGC1B Products
Product
Figures
Specificity
Applications
Price
Anti-PGC1 beta/PPARGC1B Picoband® Antibody
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02933-1
100 μg/vial
Cat # A02933-1
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M02933-1
20μL, 40μL, 100μL, 200μL
Cat # M02933-1
20μL, 40μL, 100μL, 200μL
PPARGC1B Overview
Facts about Peroxisome proliferator-activated receptor gamma coactivator 1-beta.
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B)
Plays a part of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids.
May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as indicated by increased cerebral oxygen consumption and mitochondrial amount when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.
Gene Information
| Human | |
|---|---|
| Gene Name: | PPARGC1B |
| Uniprot: | Q86YN6 |
| Entrez: | 133522 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DKFZp686C1790; ERRL1; PERCFLJ14284; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC1; PGC1Bgamma, coactivator 1, beta; PPARGC1
Molecular Weight
Mass (kDA):
113.222 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q32 |
| Sequence: | 5; NC_000005.10 (149730302..149857861) |
Tissue Specificity
Ubiquitous with higher expression in heart, brain and skeletal muscle.
Subcellular Localizations
Nucleus.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Insulin Resistance
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Neoplasms
- Insulin Sensitivity
- Mammary Neoplasms
- Inflammation
- Cardiomyopathies
- Exhaustion
- Systemic Infection
Pathways
- Oxidative Phosphorylation
- Pathogenesis
- Energy Homeostasis
- Gluconeogenesis
- Glycolysis
- Transport
- Glucose Homeostasis
- Cell Proliferation
- Cell Growth
- Fatty Acid Oxidation
- Osteoclast Differentiation
- Acute Inflammatory Response
- Osteoclast Development
PTMs
- Phosphorylation
Research Areas
- Lipid and Metabolism
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPARGC1B
bosterbio.com/bosterbio-gene-info-cards/PPARGC1B
References
PMID: 11854298 by Kressler D., et al. The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha.
PMID: 12678921 by Meirhaeghe A., et al. Characterization of the human, mouse and rat PGC1 beta (peroxisome- proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.
3 Publications of Boster PPARGC1B Antibodies & ELISA Kits
- PubMed ID: 10.1111/j.1476-5381.2010.00900.x, Troglitazone induces cytotoxicity in part by promoting the degradation of peroxi...
- PubMed ID: 10.1016/j.bbamcr.2011.03.017, Mitogen-activated protein kinase kinases promote mitochondrial biogenesis in par...
- PubMed ID: 32343674, Liu Y,Bai H,Guo F,Thai PN,Luo X,Zhang P,Yang C,Feng X,Zhu D,Guo J,Liang P,Xu Z,Y...
*More publications can be found for each product on its corresponding product page