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PPCS Antibodies

AND PPCS ELISA kits, PPCS Proteins

Many biological assays use antibodies to detect PPCS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPCS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPCS antibodies...

We validate the specificity of these antibodies to PPCS by testing them on tissues known to express PPCS positively and negatively. Browse below to find the PPCS antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPCS Infographic by Boster Bio

PPCS protein infographic

All PPCS Products

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Figures

Specificity

Applications

Price

Anti-PPCS Antibody Picoband®

3 Q&As

Western blot analysis of PPCS using anti-PPCS antibody (A05567-1)

Western blot analysis of PPCS using anti-PPCS antibody (A05567-1)

IHC analysis of PPCS using anti-PPCS antibody (A05567-1)

Flow Cytometry analysis of A431 cells using anti-PPCS antibody (A05567-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # A05567-1
100 μg/vial

Anti-PPCS Antibody Picoband® (monoclonal, 7G13)

1 Q&As

Western blot analysis of PPCS using anti-PPCS antibody (M05567)

Western blot analysis of PPCS using anti-PPCS antibody (M05567)

IHC analysis of PPCS using anti-PPCS antibody (M05567)

IHC analysis of PPCS using anti-PPCS antibody (M05567)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M05567
100 μg/vial

Human PPCS Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE

$250
Cat # PROTQ9HAB8
Starting from 20ug

Anti-PPCS Rabbit Monoclonal Antibody

Western blot analysis of PPCS expression in SH-SY5Y cell lysate

Western blot analysis of PPCS expression in SH-SY5Y cell lysate

Human

IF, IHC, ICC, WB

$370
Cat # M05567-1
100 μl/vial

PPCS Overview

Facts about Phosphopantothenate--cysteine ligase.

PPCS 3D structure

PPCS 3D structure. Source: alphafold

Phosphopantothenate--cysteine ligase (PPCS)

Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. .

Gene Information

Human
Gene Name:	PPCS
Uniprot:	Q9HAB8
Entrez:	79717

Gene Information

Family

Belongs to:

PPC synthetase family

Family

Alternative Names

FLJ11838; MGC117357; phosphopantothenoylcysteine synthetase; PPC synthetase

Molecular Weight

Mass (kDA):
34.005 kDA

Molecular Weight

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (42456341..42473381)

Diseases

Brain Injuries
Post-concussion Syndrome
Craniocerebral Trauma
Pain
Traumatic Brain Injury
Hepatitis
Liver Diseases
Closed Head Injuries
Aneurysm
Hepatitis, Alcoholic
Hepatitis, Autoimmune
Brain Injury, Chronic

Intracranial Aneurysm
Dementia
Dizziness
Physical Disability
Edema
Alcoholic Liver Diseases

Disease

Pathways

Tissue Morphogenesis
Coagulation
Delamination
Dna Repair
Gluconeogenesis
Localization

Oogenesis

Pathways

PTMs

Carboxylation

Phosphorylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPCS

References

PMID: 11923312 by Daugherty M., et al. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.

PMID: 12906824 by Manoj N., et al. Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution.