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- Table of Contents
Periplakin Antibodies
AND PPL ELISA kits, Periplakin Proteins
Many biological assays use antibodies to detect Periplakin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Periplakin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Periplakin antibodies...
Designing a Western blot for Periplakin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PPL Western Blot GuidePPL Infographic by Boster Bio
All PPL Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02098-1
100 μg/vial
Cat # A02098-1
100 μg/vial
PPL Overview
Facts about Periplakin.
Periplakin (PPL)
Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.
May act as a localization signal in PKB/AKT-mediated signaling. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PPL |
| Uniprot: | O60437 |
| Entrez: | 5493 |
Family
| Belongs to: |
|---|
| plakin or cytolinker family |
Alternative Names
190 kDa paraneoplastic pemphigus antigen; 195 kDa cornified envelope precursor protein; KIAA0568; MGC134872; periplakin
Molecular Weight
Mass (kDA):
204.747 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p13.3 |
| Sequence: | 16; NC_000016.10 (4882507..4937148, complement) |
Tissue Specificity
Expressed in stratified squamous epithelia and in some other epithelia.
Subcellular Localizations
Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Nucleus. Mitochondrion. Associated with desmosomes and intermediate filaments.
Diseases
- Allergy
- Lung Diseases
- Lung Diseases, Obstructive
- Malignant Neoplasms
- Penicillin Allergy
- Chronic Obstructive Airway Disease
- Neoplasms
- Lymphoma
- Lung Neoplasms
- Cardiovascular Diseases
- Hypertensive Disease
Interacting Proteins
- AHCYL1
- AKT1
- ALAS1
- ANXA9
- BTN3A1
- RAB3IP
- RALBP1
- TRAF2
- TRIM27
- TSC22D4
Pathways
- Hypersensitivity
- Transport
- Localization
- Pathogenesis
- Secretion
- Coagulation
- Sensitization
- Cell Adhesion
- Reflex
- Anaphylaxis
- Innervation
- Muscle Contraction
- Inflammatory Response
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Acylation
- Deacetylation
- Amination
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPL
bosterbio.com/bosterbio-gene-info-cards/PPL
References
PMID: 9412476 by Ruhrberg C., et al. Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.
PMID: 9521878 by Aho S., et al. cDNA cloning, mRNA expression, and chromosomal mapping of human and mouse periplakin genes.