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- Table of Contents
PPP2CB Antibodies
AND PPP2CB ELISA kits, PPP2CB Proteins
Many biological assays use antibodies to detect PPP2CB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2CB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2CB antibodies...
Designing an IHC experiment for PPP2CB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PPP2CB IHC GuidePPP2CB Infographic by Boster Bio
All PPP2CB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M07661
100 μl
Cat # M07661
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01893-2
20μL, 40μL, 100μL, 200μL
Cat # M01893-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat, Zebrafish
IP, IHC, ICC, WB
$405
Cat # A07661-1
100ul
Cat # A07661-1
100ul
PPP2CB Overview
Facts about Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform.
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB)
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PPP2CB |
| Uniprot: | P62714 |
| Entrez: | 5516 |
Family
| Belongs to: |
|---|
| PPP phosphatase family |
Alternative Names
EC 3.1.3.16; PP2Abeta; PP2A-beta; PP2CB; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Molecular Weight
Mass (kDA):
35.575 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p12 |
| Sequence: | 8; NC_000008.11 (30785616..30812818, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
Diseases
- Malignant Neoplasms
- Carcinoma
- Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Werner Syndrome
- Malignant Neoplasm Of Urinary Bladder
- Mammary Neoplasms
- Bladder Neoplasm
- Carcinoma, Transitional Cell
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Colonic Neoplasms
Interacting Proteins
- AXIN2
- IGBP1
- STRIP1
Pathways
- Cell Cycle
- Localization
- Meiosis
- Cell Cycle Arrest
PTMs
- Phosphorylation
Research Areas
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP2CB
bosterbio.com/bosterbio-gene-info-cards/PPP2CB
References
PMID: 2849765 by Hemmings B.A., et al. The nucleotide sequence of the cDNA encoding the human lung protein phosphatase 2A beta catalytic subunit.
PMID: 2837763 by Arino J., et al. Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.