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- Table of Contents
PPT1 Antibodies
AND PPT1 ELISA kits, PPT1 Proteins
Many biological assays use antibodies to detect PPT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPT1 antibodies...
Designing a Western blot for PPT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PPT1 Western Blot GuideDesigning an IHC experiment for PPT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PPT1 IHC GuidePPT1 Infographic by Boster Bio
All PPT1 Products
Product
Figures
Specificity
Applications
Price
Anti-PPT1 Antibody Picoband® (monoclonal, 10F3)
1 Citations
Human
Flow Cytometry, IHC, WB
$370
Cat # M02690
100 μg/vial
Cat # M02690
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # PB9781
100 μg/vial
Cat # PB9781
100 μg/vial
PPT1 Overview
Facts about Palmitoyl-protein thioesterase 1.
Palmitoyl-protein thioesterase 1 (PPT1)
Removes thioester-linked fatty acyl groups like palmitate from modified cysteine residues in proteins or peptides through lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons (PubMed:8816748).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PPT1 |
| Uniprot: | P50897 |
| Entrez: | 5538 |
Family
| Belongs to: |
|---|
| palmitoyl-protein thioesterase family |
Alternative Names
ceroid-palmitoyl-palmitoyl-protein thioesterase 1; CLN1EC 3.1.2.22; INCL; Palmitoyl-protein hydrolase 1; palmitoyl-protein thioesterase 1; PPT; PPT-1
Molecular Weight
Mass (kDA):
34.193 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.2 |
| Sequence: | 1; NC_000001.11 (40071461..40097252, complement) |
Subcellular Localizations
Lysosome. Secreted.
Diseases
- Neuronal Ceroid-lipofuscinoses
- Infantile Neuronal Ceroid Lipofuscinosis
- Neurodegenerative Disorders
- Nerve Degeneration
- Juvenile Neuronal Ceroid Lipfuscinosis
- Lysosomal Storage Diseases
- Nervousness
- Blind Vision
- Epilepsy
- Atrophy
- Late-infantile Neuronal Ceroid Lipfuscinosis
Pathways
- Pathogenesis
- Localization
- Cell Death
- Transport
- Protein Palmitoylation
- Reverse Transcription
- Endocytosis
- Transposition
- Fermentation
- Glycosylation
- Hyperphosphorylation
- Immune Response
- Neuroprotection
PTMs
- Palmitoylation
- Phosphorylation
- Cleavage
- Dephosphorylation
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPT1
bosterbio.com/bosterbio-gene-info-cards/PPT1
References
PMID: 7637805 by Vesa J., et al. Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis.
PMID: 8633062 by Crews C.M., et al. Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.