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- Table of Contents
Facts about Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein.
May function downstream of heterotrimeric G proteins in neutrophils. .
| Human | |
|---|---|
| Gene Name: | PREX1 |
| Uniprot: | Q8TCU6 |
| Entrez: | 57580 |

| Belongs to: |
|---|
| No superfamily |

KIAA1415; phosphatidylinositol 34,5-trisphosphate-dependent Rac exchanger 1 protein; phosphatidylinositol-34,5-trisphosphate-dependent Rac exchange factor 1; PRex1; P-Rex1; ptdIns(34,5)-dependent Rac exchanger 1
Mass (kDA):
186.203 kDA

| Human | |
|---|---|
| Location: | 20q13.13 |
| Sequence: | 20; NC_000020.11 (48624252..48827999, complement) |
Cytoplasm, cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.





PMID: 11955434 by Welch H.C.E., et al. P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine- nucleotide exchange factor for Rac.