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- Table of Contents
PRMT7 Antibodies
AND PRMT7 ELISA kits, PRMT7 Proteins
Many biological assays use antibodies to detect PRMT7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRMT7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRMT7 antibodies...
Designing a Western blot for PRMT7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PRMT7 Western Blot GuideDesigning an IHC experiment for PRMT7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PRMT7 IHC GuidePRMT7 Infographic by Boster Bio
All PRMT7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05485-2
100 µg/vial
Cat # A05485-2
100 µg/vial
PRMT7 Overview
Facts about Protein arginine N-methyltransferase 7.
Protein arginine N-methyltransferase 7 (PRMT7)
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Especially mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); these methylation being required for its assembly and biogenesis of snRNP core particles.
Especially mediates the symmetric dimethylation of histone H4'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL in the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these websites.
Gene Information
| Human | |
|---|---|
| Gene Name: | PRMT7 |
| Uniprot: | Q9NVM4 |
| Entrez: | 54496 |
Family
| Belongs to: |
|---|
| class I-like SAM-binding methyltransferase superfamily |
Alternative Names
[Myelin basic protein]-arginine N-methyltransferase PRMT7; EC 2.1.1; EC 2.1.1.125; EC 2.1.1.126; FLJ10640; Histone-arginine N-methyltransferase PRMT7; KIAA1933EC 2.1.1.-; myelin basic protein-arginine N-methyltransferase; protein arginine methyltransferase 7; protein arginine N-methyltransferase 7
Molecular Weight
Mass (kDA):
78.459 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q22.1 |
| Sequence: | 16; NC_000016.10 (68310982..68360876) |
Subcellular Localizations
Cytoplasm, cytosol. Nucleus.
Diseases
- Cell Transformation, Neoplastic
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Anaplasia
- Kabuki Make-up Syndrome
- Neoplasm Metastasis
- Mastitis-metritis-agalactia Syndrome
- Malignant Neoplasm Of Breast
- Neurotoxicity Syndromes
- Single Gene Defect
- Kidney Failure
Pathways
- Methylation
- Dna Repair
- Localization
- Protein Methylation
- Cell Cycle
- Dedifferentiation
- Transport
- Cell Development
- Regulation Of Gene Expression
- Liver Development
- Translational Elongation
- Histone Phosphorylation
- Germ Cell Development
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRMT7
bosterbio.com/bosterbio-gene-info-cards/PRMT7
References
PMID: 15044439 by Miranda T.B., et al. PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity.
PMID: 15494416 by Lee J.-H., et al. PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine.