This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
PRPF31 Antibodies
AND PRPF31 ELISA kits, PRPF31 Proteins
Many biological assays use antibodies to detect PRPF31, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRPF31 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRPF31 antibodies...
Designing an IHC experiment for PRPF31? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PRPF31 IHC GuidePRPF31 Infographic by Boster Bio
All PRPF31 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M03137
100 μl/vial
Cat # M03137
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03137-1
100 µg/vial
Cat # A03137-1
100 µg/vial
PRPF31 Overview
Facts about U4/U6 small nuclear ribonucleoprotein Prp31.
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31)
Involved in pre-mRNA splicing as part of the spliceosome (PubMed:11867543, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PRPF31 |
| Uniprot: | Q8WWY3 |
| Entrez: | 26121 |
Family
| Belongs to: |
|---|
| PRP31 family |
Alternative Names
DKFZp566J153; hPrp31; NY-BR-99; Pre-mRNA-processing factor 31; Protein 61K; PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae); PRP31 pre-mRNA processing factor 31 homolog (yeast); PRP31RP11; Serologically defined breast cancer antigen NY-BR-99; U4/U6 small nuclear ribonucleoprotein Prp31; U4/U6 snRNP 61 kDa protein
Molecular Weight
Mass (kDA):
55.456 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.42 |
| Sequence: | 19; NC_000019.10 (54115706..54131719) |
Tissue Specificity
Ubiquitously expressed.
Subcellular Localizations
Nucleus. Nucleus speckle. Nucleus, Cajal body. Predominantly found in speckles and in Cajal bodies.
Diseases
- Retinitis Pigmentosa
- Retinal Degeneration
- Haploinsufficiency
- Blind Vision
- Hereditary Diseases
- Night Blindness
- Cytogenetic Abnormality
- Retinal Diseases
- Dystrophy
- De Novo Mutation
- Abnormal Degeneration
Pathways
- Rna Splicing
- Mrna Splicing
- Pathogenesis
- Localization
- Protein Phosphorylation
- Transport
- Cell Proliferation
- Circadian Rhythm
- Nuclear Transport
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPF31
bosterbio.com/bosterbio-gene-info-cards/PRPF31
References
PMID: 11867543 by Makarova O.V., et al. Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 tri-snRNP formation and pre-mRNA splicing.
PMID: 12747765 by Scanlan M.J., et al. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.