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- Table of Contents
Trypsin-1 Antibodies
AND PRSS1 ELISA kits, Trypsin-1 Proteins
Many biological assays use antibodies to detect Trypsin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Trypsin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Trypsin-1 antibodies...
Designing a Western blot for Trypsin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PRSS1 Western Blot GuidePRSS1 Infographic by Boster Bio
All PRSS1 Products
Product
Figures
Specificity
Applications
Price
Human KLK8/Kallikrein-8 ELISA Kit PicoKine®
3 Citations
Human
ELISA
$750
Cat # EK0819
96 wells/kit, with removable strips.
Cat # EK0819
96 wells/kit, with removable strips.
Anti-PDIA6 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03813-2
100 μg/vial
Cat # A03813-2
100 μg/vial
Anti-LONP1/Lon Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A03808-2
100 μg/vial
Cat # A03808-2
100 μg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01802-3
100 μg/vial
Cat # A01802-3
100 μg/vial
Human
$960
Cat # LS008492
20 µg, 100 µg
Cat # LS008492
20 µg, 100 µg
PRSS1 Overview
Facts about Trypsin-1.
Trypsin-1 (PRSS1)
Has Action against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec.
The single-chain form is more active than the two- chain form against all of these substrates..
Gene Information
| Human | |
|---|---|
| Gene Name: | PRSS1 |
| Uniprot: | P07477 |
| Entrez: | 5644 |
Family
| Belongs to: |
|---|
| peptidase S1 family |
Alternative Names
Beta-trypsin; Cationic trypsinogen; digestive zymogen; DKFZp779A0837; EC 3.4.21; EC 3.4.21.4; FLJ57296; MGC120175; MGC149362; nonfunctional trypsin 1; protease, serine, 1 (trypsin 1); PRSS1; PTRYI; Serine protease 1; TRP1; TRY1beta-trypsin; TRY4; Trygn16; TRYP1; Trypsin 1; Trypsin I; trypsin-1; Trypsinogen 1; trypsinogen A
Molecular Weight
Mass (kDA):
26.558 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q34 |
| Sequence: | 7; NC_000007.14 (142740235..142753076) |
Subcellular Localizations
Secreted, extracellular space.
Diseases
- Pancreatitis
- Pancreatitis, Chronic
- Malignant Neoplasms
- Fibrosis
- Malignant Neoplasm Of Pancreas
- Cystic Fibrosis
- Pancreatic Neoplasm
- Acute Pancreatitis
- Diabetes Mellitus
- Pain
- Pancreatitis, Alcoholic
- Adenocarcinoma
Pathways
- Pathogenesis
- Trypsinogen Activation
- Secretion
- Autolysis
- Inflammatory Response
- Gene Conversion
- Transport
- Localization
- Cell Death
- Intein-mediated Protein Splicing
- Programmed Cell Death
- Fertilization
- Immune Response
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRSS1
bosterbio.com/bosterbio-gene-info-cards/PRSS1
References
PMID: 3011602 by Emi M., et al. Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.
PMID: 8650574 by Rowen L., et al. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.
2 Publications of Boster Trypsin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1186/s13195-021-00945-x, Is kallikrein-8 a blood biomarker for detecting amnestic mild cognitive impairme...
- PubMed ID: 29505099 , Higher levels of kallikrein-8 in female brain may increase the risk for Alzheime...
*More publications can be found for each product on its corresponding product page