Prostaglandin E synthase Antibodies

AND PTGES ELISA kits, Prostaglandin E synthase Proteins

Many biological assays use antibodies to detect Prostaglandin E synthase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prostaglandin E synthase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prostaglandin E synthase antibodies...

We validate the specificity of these antibodies to Prostaglandin E synthase by testing them on tissues known to express PTGES positively and negatively. Browse below to find the PTGES antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTGES Infographic by Boster Bio

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Anti-PGE synthase (I79) PTGES Antibody

Western blot (WB) analysis of PGE synthase (I79) polyclonal antibody at 1:500 dilution
Lane1:NIH-3T3 whole cell lysate(40ug)
Lane2:Hela whole cell lysate(40ug)
Lane3:H9C2 whole cell lysate(40ug)
Lane4:SP2/0 whole cell lysate(40ug)

Human, Mouse, Rat

$405
Cat # A02587
100ul

PTGES Overview

Facts about Prostaglandin E synthase.

PTGES 3D structure. Source: alphafold

Prostaglandin E synthase (PTGES)

Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). .

Gene Information

Human
Gene Name:	PTGES
Uniprot:	O14684
Entrez:	9536

Family

Belongs to:

MAPEG family

Alternative Names

EC 5.3.99.3; MGC10317; MGST1L1MGST1-like 1; MGST1-L1mPGES-1; MGST-IV; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; MPGES; MPGES1; MPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGESmicrosomal prostaglandin E synthase-1; PIG12glutathione S-transferase 1-like 1; PP102; PP1294; prostaglandin E synthase; TP53I12; tumor protein p53 inducible protein 12

Molecular Weight

Mass (kDA):
17.102 kDA

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (129738349..129753042, complement)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Inflammation
Endometrial Polyp
Malignant Neoplasms
Neoplasms
Tumor Angiogenesis
Carcinoma
Hypoxia
Hypertrophy
Infarction
Inflammatory Response
Myocardial Infarction
Cerebrovascular Accident
Lymphoma

Adenocarcinoma
Mycoplasma Pneumonia
Asthma
Tissue Adhesions
Hypertensive Disease
Menopausal Symptom
Hyperplasia

Pathways

Secretion
Angiogenesis
Cell Proliferation
Parturition
Ovulation
Pathogenesis
Inflammatory Response
Cell Cycle
Cell Migration
Cell Motility
Luteolysis
Dna Methylation
Immune Response

Epiboly
Feeding Behavior
Meiosis
Gastrulation
Menopause
Methylation
Decidualization

PTMs

Methylation

Demethylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGES

References

PMID: 9305847 by Polyak K., et al. A model for p53-induced apoptosis.

PMID: 10377395 by Jakobsson P.-J., et al. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target.