Securin-2 Antibodies

AND PTTG2 ELISA kits, Securin-2 Proteins

Many biological assays use antibodies to detect Securin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Securin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Securin-2 antibodies...

We validate the specificity of these antibodies to Securin-2 by testing them on tissues known to express PTTG2 positively and negatively. Browse below to find the PTTG2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTTG2 Infographic by Boster Bio

All PTTG2 Products

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Product

Figures

Specificity

Applications

Price

Anti-PTTG2 Antibody (Center)

Fluorescent confocal image of MCF-7 cell stained with PTTG2 Antibody (Center)

Human

IF, WB

$299
Cat # A15119
80 µl

Securin 2 (PTTG2) (NM_006607) Human Over-expression Lysate

Human

$628
Cat # LS010744
20 µg, 100 µg

PTTG2 Overview

Facts about Securin-2.

PTTG2 3D structure. Source: alphafold

Securin-2 (PTTG2)

Gene Information

Human
Gene Name:	PTTG2
Uniprot:	Q9NZH5
Entrez:	10744

Family

Belongs to:

securin family

Alternative Names

pituitary tumor-transforming 2; Pituitary tumor-transforming gene 2 protein; securin-2

Molecular Weight

Mass (kDA):
22.302 kDA

Genomic Context


Human

Location:	4p14
Sequence:	4; NC_000004.12 (37960398..37961128)

Tissue Specificity

Expressed at low levels in the pituitary, liver, spleen, prostate, testis, ovary, small intestine and colon. Also expressed in various pituitary, testicular, liver and ovarian tumors.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Neoplasms
Liver Carcinoma
Pituitary Diseases
Metaplastic Cell Transformation
Liver Neoplasms
Pituitary Neoplasms
Malignant Neoplasm Of Liver

Colorectal Cancer
Carcinoma

Pathways

Gene Silencing
Induction Of Apoptosis
Cell Growth

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTTG2

References

PMID: 10084610 by Prezant T.R., et al. An intronless homolog of human proto-oncogene hPTTG is expressed in pituitary tumors: evidence for hPTTG family.

PMID: 10806349 by Chen L., et al. Identification of the human pituitary tumor transforming gene (hPTTG) family: molecular structure, expression, and chromosomal localization.